Michael Houghton - researchr alias

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Viewing Publication 1 - 6 from 6

2020

Application of Molecular Dynamics Simulations to the Design of Nucleotide Inhibitors Binding to Norovirus PolymeraseHolly Freedman, Juthika Kundu, Egor Petrovitch Tchesnokov, John Lok Man Law, James A. Nieman, Raymond F. Schinazi, D. Lorne Tyrrell, Matthias Gotte, Michael Houghton. jcisd, 60(12):6566-6578, 2020. [doi]

2015

A Refined Model of the HCV NS5A Protein Bound to Daclatasvir Explains Drug-Resistant Mutations and Activity against Divergent GenotypesKhaled H. Barakat, Anwar Anwar-Mohamed, Jack A. Tuszynski, Morris J. Robins, D. Lorne Tyrrell, Michael Houghton. jcisd, 55(2):362-373, 2015. [doi]

2014

Rational Drug Design: One Target, Many Paths to ItKhaled H. Barakat, Michael Houghton, D. Lorne Tyrrell, Jack A. Tuszynski. ijcmam, 4(1):59-85, 2014. [doi]

2013

Detailed Computational Study of the Active Site of the Hepatitis C Viral RNA Polymerase to Aid Novel Drug DesignKhaled H. Barakat, John Law, Alessio Prunotto, Wendy C. Magee, David H. Evans, D. Lorne Tyrrell, Jack A. Tuszynski, Michael Houghton. jcisd, 53(11):3031-3043, 2013. [doi]

1992

Group specific sequences and conserved secondary structures at the 3 end of HCV genome and its implication for viral replicationJang H. Han, Michael Houghton. nar, 20(13):3520, 1992.

1980

The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptaseMichael Houghton, M. A. Easton, A. G. Stewart, J. C. Smith, S. M. Doel, G. H. Catlin, H. M. Lewis, T. P. Patel, J. S. Emtage, N. H. Carey, Andrew C. G. Porter. nar, 8(13):2885-2894, 1980.

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