An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins

Greet De Baets, Joke Reumers, Javier Delgado Blanco, JoaquĆ­n Dopazo, Joost Schymkowitz, Frederic Rousseau. An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins. PLoS Computational Biology, 7(6), 2011. [doi]

Abstract

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