Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3)

Anders Poulsen, Anthony William, Stéphanie Blanchard, Angeline Lee, Harish Nagaraj, Haishan Wang, Eeling Teo, Evelyn Tan, Kee Chuan Goh, Brian Dymock. Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3). Journal of Computer-Aided Molecular Design, 26(4):437-450, 2012. [doi]

@article{PoulsenWBLNWTTGD12,
  title = {Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3)},
  author = {Anders Poulsen and Anthony William and Stéphanie Blanchard and Angeline Lee and Harish Nagaraj and Haishan Wang and Eeling Teo and Evelyn Tan and Kee Chuan Goh and Brian Dymock},
  year = {2012},
  doi = {10.1007/s10822-012-9572-z},
  url = {http://dx.doi.org/10.1007/s10822-012-9572-z},
  researchr = {https://researchr.org/publication/PoulsenWBLNWTTGD12},
  cites = {0},
  citedby = {0},
  journal = {Journal of Computer-Aided Molecular Design},
  volume = {26},
  number = {4},
  pages = {437-450},
}