Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors

Karen A. Rossi, Jay A. Markwalder, Steven P. Seitz, Chong-Hwan Chang, Sarah Cox, Michael D. Boisclair, Leonardo Brizuela, Stephen L. Brenner, Pieter F. W. Stouten. Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors. Journal of Computer-Aided Molecular Design, 19(2):111-122, 2005. [doi]

Authors

Karen A. Rossi

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Jay A. Markwalder

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Steven P. Seitz

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Chong-Hwan Chang

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Sarah Cox

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Michael D. Boisclair

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Leonardo Brizuela

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Stephen L. Brenner

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Pieter F. W. Stouten

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