Why substrate depletion has apparent first-order kinetics in enzymatic digestion

J. Srividhya, Santiago Schnell. Why substrate depletion has apparent first-order kinetics in enzymatic digestion. Computers & Chemistry, 30(3):209-214, 2006. [doi]

@article{SrividhyaS06,
  title = {Why substrate depletion has apparent first-order kinetics in enzymatic digestion},
  author = {J. Srividhya and Santiago Schnell},
  year = {2006},
  doi = {10.1016/j.compbiolchem.2006.03.003},
  url = {http://dx.doi.org/10.1016/j.compbiolchem.2006.03.003},
  researchr = {https://researchr.org/publication/SrividhyaS06},
  cites = {0},
  citedby = {0},
  journal = {Computers & Chemistry},
  volume = {30},
  number = {3},
  pages = {209-214},
}