Leveraging Large Language Models for Cancer Variant Classification: A Comparative Study of GPT-4o, LLaMA 3, and Qwen 2.5

Kuan-Hsun Lin, Paul Chih-Hsueh Chen, Chen-Tsung Kuo, Yuan-Chia Chu, Yi-Chen Yeh. Leveraging Large Language Models for Cancer Variant Classification: A Comparative Study of GPT-4o, LLaMA 3, and Qwen 2.5. In Mowafa S. Househ, Zain Ul Abideen Tariq, Mahmood Al-Zubaidi, Uzair Shah, Elaine Huesing, editors, MEDINFO 2025 - Healthcare Smart × Medicine Deep - Proceedings of the 20th World Congress on Medical and Health Informatics, Taipei, Taiwan, 9-13 August 2025. Volume 329 of Studies in Health Technology and Informatics, pages 1728-1729, IOS Press, 2025. [doi]

Abstract

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