Integrated multiomics analysis and advanced machine learning techniques to refine molecular subtypes, stratify prognosis, characterize tumor microenvironment, and identify distinct sensitivity patterns to frontline therapies in lung squamous cell carcinoma

Shi Yan, Xu Zhang, Tongying Xu, Xiangyu Wang, Fanglin Tian, Weina Fan, Yuning Zhan, Li Cai, Ying Xing. Integrated multiomics analysis and advanced machine learning techniques to refine molecular subtypes, stratify prognosis, characterize tumor microenvironment, and identify distinct sensitivity patterns to frontline therapies in lung squamous cell carcinoma. J. Big Data, 13(1):22, December 2026. [doi]