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Penalised regression improves imputation of cell-type specific expression using RNA-seq data from mixed cell populations compared to domain-specific methods

Wei-Yu Lin, Melissa Kartawinata, Bethany R. Jebson, Restuadi Restuadi, Hannah Peckham, Anna Radziszewska, Claire T. Deakin, Coziana Ciurtin, Lucy Wedderburn, Chris Wallace 0002. Penalised regression improves imputation of cell-type specific expression using RNA-seq data from mixed cell populations compared to domain-specific methods. PLoS Computational Biology, 21(3):1012859, 2025. [doi]

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