Journal: Briefings in Bioinformatics

Volume 26, Issue 5

0 -- 0Hongxu Zhu, Amir Asiaee, Leila Azinfar, Jun Li, Han Liang, Ehsan Irajizad, Kim-Anh Do, James P. Long. in-silico perturbation methods in identifying differentially expressed genes
0 -- 0Yinyin Gong, Rui Li 0019, Yan Liu 0032, Jilong Wang 0002, Danny Z. Chen, Chee-Keong Kwoh 0001. DeepPhosPPI: a deep learning framework with attention-CNN and transformer for predicting phosphorylation effects on protein-protein interactions
0 -- 0Yu Wang, Haichun Yang, Ruining Deng, Yuankai Huo, Qi Liu 0024, Yu Shyr, Shilin Zhao. stImage: a versatile framework for optimizing spatial transcriptomic analysis through customizable deep histology and location informed integration
0 -- 0Rami Zakh, Alexander Churkin, Marina Parr, Tamir Tuller, Ohad Etzion, Harel Dahari, Danny Barash. The bioinformatics of the finding that the hepatitis delta virus RNA editing mechanism by a conformational switch exists in genotype 7 in addition to genotype 3
0 -- 0Linyang Jiang, Xiaodi Yang, Xiaokun Guo, Dianke Li, Jiajun Li, Stefan Wuchty, Wenyu Shi, Ziding Zhang. Graph neural network integrated with pretrained protein language model for predicting human-virus protein-protein interactions
0 -- 0Yingxuan Ren, Fengtao Ren, Bo Yang 0041. Multi-layer matrix factorization for cancer subtyping using full and partial multi-omics dataset
0 -- 0John Lee, Canh Hao Nguyen, Hiroshi Mamitsuka. Beyond rigid docking: deep learning approaches for fully flexible protein-ligand interactions
0 -- 0Geng-Ming Hu, Hsin Wei Chen, Chi-Ming Chen. Mapping cancer heterogeneity: a consensus network approach to subtypes and pathways
0 -- 0Guosheng Gu, Haowei Wu, Haojie Han, Zhiyi Lin, Yuping Sun, Guobo Xie, Qing Su, Zhenguo Liu. MVSGDR: multi-view stacked graph convolutional network for drug repositioning
0 -- 0Youna Cho, Erin Kim, Minyoung Kim, Mina Rho. DeepMobilome: predicting mobile genetic elements using sequencing reads of microbiomes
0 -- 0Yanwen Shao, Zhihao Guo, Jinpeng Chen, Runsheng Li. SLRanger: an integrated approach for spliced leader detection and operon prediction using long RNA reads
0 -- 0Hao Wang, Guoqing Hu, Stephen S.-T. Yau. Energy entropy vector: a novel approach for efficient microbial genomic sequence analysis and classification
0 -- 0Junxin Li, Chao Zhang, Wei Xia, Hei Wun Kan, Kaifang Huang, Sai Li, Mark Akinola Ige, Qiuliyang Yu, Jiawei Zhao, Xiaochun Wan, John Z. H. Zhang, Haiping Zhang. Significantly enhancing human antibody affinity via deep learning and computational biology-guided single-point mutations
0 -- 0Kailun Bai, Belaid Moa, Xiaojian Shao, Xuekui Zhang. scSorterDL: a deep neural network-enhanced ensemble LDAs for single cell classifications
0 -- 0Junlei Yu, Wenjia Gao, Siqi Chen 0001, Ronglin Lu, Jianbo Qiao, Junru Jin, Leyi Wei, Hua Shi, Zilong Zhang, Feifei Cui, Xinbo Jiang, Zhongmin Yan. MCAMEF-BERT: an efficient deep learning method for RNA N7-methylguanosine site prediction via multi-branch feature integration
0 -- 0Yaowu Zhang, Xiu Jin, Xiaodan Zhang. GCNMF-SDA: predicting snoRNA-disease associations based on graph convolution and non-negative matrix factorization
0 -- 0Shenjie Wang, Xiaonan Wang, Xiaoyan Zhu, Xuwen Wang, Yuqian Liu, Minchao Zhao, Zhili Chang, Yang Shao, Haitao Zhang, Shuanying Yang, Jiayin Wang. TMBquant: an explainable AI-powered caller advancing tumor mutation burden quantification across heterogeneous samples
0 -- 0Xiang Li, Wei Peng, Xiaolei Zhu 0001. Predicting nucleic acid binding sites by attention map-guided graph convolutional network with protein language embeddings and physicochemical information
0 -- 0Carolin Charlotte Wendling, Marie Vasse, Sébastien Wielgoss. Phage quest: a beginner's guide to explore viral diversity in the prokaryotic world
0 -- 0Huayu Zhong, Juanji Wang, Xiaoxiao Liu, Xiaoyun Wei, Chengcheng Zhou, Taiyan Zou, Xin Han, Lingyun Mo, Wenling Qin, Yonghong Zhang. A multi-dimensional computational framework of drug-induced hepatotoxicity: integrating molecular structure features with disease pathogenesis

Volume 26, Issue 4

0 -- 0Daehun Bae, Minsang Kim, Jiwon Seo, Hojung Nam. AI-guided discovery and optimization of antimicrobial peptides through species-aware language model
0 -- 0Ana R. Baião, Zhaoxiang Cai, Rebecca C. Poulos, Phillip J. Robinson, Roger R. Reddel, Qing Zhong, Susana Vinga, Emanuel Gonçalves. A technical review of multi-omics data integration methods: from classical statistical to deep generative approaches
0 -- 0Yijun Mao, Xingcheng Peng, Jian Weng 0001, Rongjin Jiang, Yingjie Kuang, Jiasi Weng 0001, Rui Pang, Yunyan Xiong, Wanrong Gu, Deyu Tang. MDNN: memetic deep neural network for genomic prediction
0 -- 0Keichin N. G. Ensemble learning methods and heterogeneous graph network fusion: building drug-gene-disease triple association prediction models
0 -- 0Wei Zhang, Bowen Shao, Wenrui Li, Wenbo Guo, Jiaxin Lyu, Guangyi Chen, Chuanyuan Wang, Zhi-Ping Liu. Inferring cell-type-specific gene regulatory network from cellular transcriptomics data with GeneLink+
0 -- 0Laiyi Fu, Yangyi Zhou, Hongqiang Lyu, Hequan Sun. Dual balanced augmented topological noncoding RNA disease triplet association in heterogeneous graphs
0 -- 0Maria Sindeeva, Alexander Telepov, Nikita Ivanisenko, Tatiana I Shashkova, Kuzma Khrabrov, Artem Tsypin, Artur Kadurin, Olga L. Kardymon. AFToolkit: a framework for molecular modeling of proteins with AlphaFold-derived representations
0 -- 0Zhi Ran, Meilin Mu, Shaofeng Lin, Tao Wang, Jing Zeng, Lan Kuang, Kunqi Chen, Shengbao Suo, Kai Yuan, Hao-Dong Xu. Deciphering the MHC immunopeptidome of human cancers with Ligand.MHC atlas
0 -- 0Hansika Weerasena, Aruna Jayasena, Christina Boucher, Prabhat Mishra 0001. Formal verification of bioinformatics software using model checking and theorem proving
0 -- 0Kuang-Cheng Hsu, Pei-Hua Wang, Bo-Han Su, Yufeng Jane Tseng. A robust and interpretable graph neural network-based protocol for predicting p-glycoprotein substrates
0 -- 0Zhi Zhang, Qiucheng Sun, Chunyan Wang, Songrun Jiang. scGGC: a two-stage strategy for single-cell clustering through cellular gene pathway construction
0 -- 0Junlong Liu, Jiaming Xiao, Xunwen Su, Yonglin Wang. Deep learning-enhanced clustering and classification of protein molecule tertiary structures using weighted distance matrices
0 -- 0Genereux Akotenou, Achraf El Allali. Genomic language models (gLMs) decode bacterial genomes for improved gene prediction and translation initiation site identification
0 -- 0Bin Lian, Haohui Zhang, Tao Wang 0082, Yongtian Wang, Xuequn Shang 0001, N. Ahmad Aziz, Jialu Hu. Inference of gene coexpression networks from single-cell transcriptome data based on variance decomposition analysis
0 -- 0Jiani Ma, Zhikang Wang, Cen Tong, Qi Yang, Lin Zhang 0015, Hui Liu. pMHChat, characterizing the interactions between major histocompatibility complex class II molecules and peptides with large language models and deep hypergraph learning
0 -- 0Ahmed Debit, Christophe Poulet, Claire Josse, Guy Jerusalem, Chloé-Agathe Azencott, Vincent Bours, Kristel Van Steen. Assessing Random Forest self-reproducibility for optimal short biomarker signature discovery
0 -- 0Sunghong Park, Doyoon Kim, Ji-Hye Choi, Changhyung Hong, Sang Joon Son, Hyunwoong Roh, Hyunjung Shin, Hyun Goo Woo. NeuroFANN: identification of neuropathological subtypes in dementia with plasma proteins by using functionally annotated neural network
0 -- 0Catalina Gonzalez-Gomez, Manuel Rosa Calatrava, Julien Fouret. Reconciling multiple connectivity-based systems biology methods for drug repurposing
0 -- 0Shanyang Ding, Dongjiang Niu, Xiaofeng Wang, Zhixin Zhang, Qunhao Zhang, Jun Xiao, Zhen Li. MAPTrans: mutual attention transformer with dynamic meta-path pruning for drug repositioning
0 -- 0Qirui Zhou, Chaowen Li, Chao Chen, Songqing Gu, Weijun Sun, Zongmeng Zhang, Yishan Cai, Yonghui Huang, Hongtao Liu, Chao Yang, Xin Chen. Path-MGCN: a pathway activity-based multi-view graph convolutional network for determining spatial domains
0 -- 0Yingzhuo Wu, Jialuo Xu, Junming Li, Jia Gu, Xuequn Shang, Xingyi Li. Deep graph convolutional network-based multi-omics integration for cancer driver gene identification
0 -- 0Ningyu Zhong, Zhihua Du. NASNet-DTI: accurate drug-target interaction prediction using heterogeneous graphs and node adaptation
0 -- 0Youshu Cheng, Geyu Zhou, HongYu Li, Xinyu Zhang, Amy Justice, Claudia Martinez, Bradley E. Aouizerat, Ke Xu, Hongyu Zhao 0003. Incorporating local ancestry information to predict genetically associated DNA methylation in admixed populations
0 -- 0Maik Wolfram-Schauerte, Thomas Vogel, Hanati Tuoken, Maria Faelth Savitski, Eric Simon, Kay Nieselt. Approaching the holistic transcriptome - convolution and deconvolution in transcriptomics
0 -- 0Syed Sabih Ur Rehman, Muhammad Ibtisam Nasar, Cristina S. Mesquita, Souhaila Al Khodor, Richard A. Notebaart, Sascha Ott, Sunil Mundra, Ramesh P. Arasardanam, Khalid Muhammad, Mohammad Tauqeer Alam. Integrative systems biology approaches for analyzing microbiome dysbiosis and species interactions
0 -- 0Wanshan Ning, Feibo Qin, Ziwei Zhou, Hang Yang, Chentan Li, Yaping Guo. HybridKla: a hybrid deep learning framework for lactylation site prediction
0 -- 0Manuel Tognon, Alisa Kumbara, Andrea Betti, Lorenzo Ruggeri, Rosalba Giugno. Benchmarking transcription factor binding site prediction models: a comparative analysis on synthetic and biological data
0 -- 0Syed Raza Abbas, Zeeshan Abbas, Arifa Zahir, Seung-Won Lee. Advancing genome-based precision medicine: a review on machine learning applications for rare genetic disorders
0 -- 0Federico García-Criado, Pedro Seoane, Elena Rojano, Juan Garcia Ranea, James Richard Perkins. Advancing edge-based clustering and graph embedding for biological network analysis: a case study in RASopathies
0 -- 0Yushu Shi, LiangLiang Zhang, Kim-Anh Do, Robert R. Jenq, Christine B. Peterson. CAT: a conditional association test for microbiome data using a permutation approach
0 -- 0Hyunmin Woo, Seong-il Eyun. Applications and techniques of single-cell RNA sequencing across diverse species
0 -- 0Yixiang Huang, Hao Jiang 0009, Wai-Ki Ching, Dong Shen. scRECL: representative ensembles with contrastive learning for scRNA-seq data clustering analysis
0 -- 0Chenwei Zhang, Anne Condon, Khanh Dao Duc. A comprehensive survey and benchmark of deep learning-based methods for atomic model building from cryo-electron microscopy density maps
0 -- 0Yijing Zhang, Shaobo Kang, Renjie Dou, Wanmei Zhang, Yuanyuan Liu, Yang Wu, Dongxue Li, Fangfang Fan, Yanyan Ping. IMOP-Cancer: identifying mutation order pairs impacting cancer phenotypes
0 -- 0Junliang Zhou, Ningji Gong, Yanjun Hu, Hong Yu 0007, Guoyin Wang 0001, Hao Wu 0062. GRANet: a graph residual attention network for gene regulatory network inference
0 -- 0Erich Kummerfeld, Leland Williams, Yinzhao Wang, Samuel T. Peters, Elizabeth Schmidt, Mickayla Dufresne-To, David Bernlohr, Paul Robbins, Sayeed Ikramuddin, Oyedele Adeyi, Linshan Laux, Grant Barthel, Steven Johnson, Jinhua Wang, Laura Niedernhofer, Andrew Nelson, Constantin Aliferis. Artifacts in spatial transcriptomics data: their detection, importance, prevalence, and prevention
0 -- 0Xinyue Cui, Lingyu Ge, Xia Chen, Zexin Lv, Suhui Wang, Xiaogen Zhou, Guijun Zhang. Beyond static structures: protein dynamic conformations modeling in the post-AlphaFold era
0 -- 0Yao Dong, Jiaxue Zhang, Jin Shi, Yushan Hu, Xiaowen Cao, Yongfeng Dong, Xuekui Zhang. scAGCI: an anchor graph-based method for cell clustering from integrated scRNA-seq and scATAC-seq data
0 -- 0Xiaofei Zhao, Lei Wei, Xuegong Zhang. Computational methods and data resources for predicting tumor neoantigens
0 -- 0Bharath Reddy Boya, Jin Hyung Lee, Jae-Mun Choi, Jintae Lee. Impact of halogenation on scaffold toxicity assessed using HD-GEM machine learning model
0 -- 0Fenglan Pang, Guangfu Xue, Wenyi Yang, Yideng Cai, Jinhao Que, Haoxiu Sun, Pingping Wang, Shuaiyu Su, Xiyun Jin, Qian Ding, Zuxiang Wang, Meng Luo 0001, Yuexin Yang, Yi Lin, Renjie Tan, Yusong Liu, Zhaochun Xu, Qinghua Jiang. TriCLFF: a multi-modal feature fusion framework using contrastive learning for spatial domain identification
0 -- 0Yile Fu, Mohamad Youness, Alessia Virzì, Xinran Song, Michiel R. L. Tubeeckx, Gilles W. De Keulenaer, Hein Heidbuchel, Vincent F. M. Segers, Karin R. Sipido, Bernard Thienpont, H. Llewelyn Roderick. Benchmarking of computational demultiplexing methods for single-nucleus RNA sequencing data
0 -- 0Romana T. Pop, Ping Han Hsieh, Tatiana Belova, Anthony Mathelier, Marieke L. Kuijjer. Gene regulatory network integration with multi-omics data enhances survival predictions in cancer
0 -- 0Wenping Xie, Jingze Liu, Chuan Wang, Jiangyuan Wang, Wenjie Han, Yousong Peng, Xiangjun Du, Jing Meng, Kang Ning, Taijiao Jiang. PREDAC-FluB: predicting antigenic clusters of seasonal influenza B viruses with protein language model embedding based convolutional neural network
0 -- 0Anjie Qiao, Yuting Chen, Junjie Xie, Weifeng Huang, Hao Zhang, Qirui Deng, Jiahua Rao, Ji Deng, Fanbo Meng, Zhen Wang 0004, Mingyuan Xu, Hongming Chen 0001, Jiancong Xie, Shuangjia Zheng, Yuedong Yang, Guo-Bo Li, Jinping Lei. A 3D pocket-aware lead optimization model with knowledge guidance and its application for discovery of new glutaminyl cyclase inhibitors
0 -- 0Maribel Pérez-Ribera, Muhammad Faizan Khan, Roger Giné, Josep M. Badia, Alexandra Junza, Oscar Yanes, Marta Sales-Pardo, Roger Guimerà. SingleFrag: a deep learning tool for MS/MS fragment and spectral prediction and metabolite annotation
0 -- 0Samantha L. Van Buren, C. Titus Brown, Tomasz Szmatola, Carrie J. Finno. A comparative review of short genetic variant databases across humans and animal species
0 -- 0Furong Qi, Qiang Huang, Yao Xuan, Yingyin Cao, Yunyun Shen, Yihan Ren, Zhe Liu, Zheng Zhang. A roadmap for T cell receptor-peptide-bound major histocompatibility complex binding prediction by machine learning: glimpse and foresight
0 -- 0Xue Liu, Jianbin Kong, Yongtao Shan, Ziyue Yang, Jiafan Miao, Yuanfei Pan, Tianyang Luo, Zhiyuan Shi, Yingmei Wang, Qinyu Gou, Chunhui Yang, Hanzong Li, Chunmei Li, Shaochuan Li, Xu Zhang, Yanni Sun, Edward C. Holmes, Deyin Guo, Mang Shi. SegFinder: an automated tool for identifying complete RNA virus genome segments through co-occurrence in multiple sequenced samples
0 -- 0Qi Zhao, Ze Li, Qian Mao, Tingwei Chen, Yiran Zhang, Bingle Li, Zheng Zhao, Xiaoya Fan. MambaCpG: an accurate model for single-cell DNA methylation status imputation using mamba
0 -- 0Hua Shi, Zhouying Li, Quan Zou, Hui Yang. Research on RNA modification in disease diagnosis and prognostic biomarkers: current status and challenges
0 -- 0Ke Wu, Changming Sun, Jie Geng, Ping Wang, Qi Dai, Leyi Wei, Ran Su. Iterative clustering algorithm G-DESC-E and pan-cancer key gene analysis based on single-cell sequencing data
0 -- 0Jing Li, Quan Zou 0001, Chao Zhan. AttenRNA: multi-scale deep attentive model with RNA feature variability analysis
0 -- 0Xuechen Mu, Long Xu, Zhenyu Huang, Jing Yan, Bocheng Shi, Yishi Wang, Binyue Liu, Kai Zhang, Ying Xu. BloodProST: prediction of blood-secretory proteins through self-training
0 -- 0Xudong Guo, Zixu Ran, Fuyi Li. Kinase-inhibitor binding affinity prediction with pretrained graph encoder and language model
0 -- 0Zhiwei Nie, Yiming Ma, Yutian Liu 0004, Xiansong Huang, Zhihong Liu, Peng Yang, Fan Xu, Feng Yin, Zigang Li, Jie Fu 0001, Zhixiang Ren, Wen-Bin Zhang, Jie Chen 0001. Predicting protein stability changes upon mutations with dual-view ensemble learning from single sequence
0 -- 0Bishal Shrestha, Zheng Wang. HiC4D-SPOT: a spatiotemporal outlier detection tool for Hi-C data
0 -- 0Anqi Lin, Junpu Ye, Chang Qi, Lingxuan Zhu, Weiming Mou, Wenyi Gan, Dongqiang Zeng, Bufu Tang, Mingjia Xiao, Guangdi Chu, Shengkun Peng, Hank Z. H. Wong, Lin Zhang, Hengguo Zhang, Xinpei Deng, Kailai Li, Jian Zhang, Aimin Jiang, Zhengrui Li, Peng Luo. Bridging artificial intelligence and biological sciences: a comprehensive review of large language models in bioinformatics
0 -- 0Ruochi Zhang, Haoran Wu, Chang Liu 0082, Qian Yang, Yuting Xiu, Kewei Li, Ningning Chen, Yu Wang 0225, Yan Wang 0028, Xin Gao 0001, Fengfeng Zhou. PepLand: a large-scale pre-trained peptide representation model for a comprehensive landscape of both canonical and non-canonical amino acids
0 -- 0Richard A. Schäfer, Rendong Yang. A comprehensive benchmark of tools for efficient genomic interval querying
0 -- 0Zhiyang Hu, Linqiang Pan, Daijun Zhang, Yannan Bin, Yansen Su. AEPMA: peptide-microbe association prediction based on autoevolutionary heterogeneous graph learning
0 -- 0Yiyou Song, Bowen Song, Daiyun Huang, Anh Nguyen, Lihong Hu, Jia Meng 0001, Yue Wang 0060. Multimodal zero-shot learning of previously unseen epitranscriptomes from RNA-seq data
0 -- 0Xiaomei Li, Alex Whan, Meredith McNeil, David Starns, Jessica Irons, Samuel C. Andrew, Rad Suchecki. A conceptual framework for human-AI collaborative genome annotation
0 -- 0Phi Le, Leah Ung, Hai Yang, Anwen Huang, Tao He, Peter Bruno, David Y. Oh, Bridget P. Keenan, Li Zhang. PepTCR-Net: prediction of multi-class antigen peptides by T-cell receptor sequences with deep learning
0 -- 0Simone Rancati, Giovanna Nicora, Laura Bergomi, Tommaso Mario Buonocore, Daniel M. Czyz, Enea Parimbelli, Riccardo Bellazzi, Marco Salemi, Mattia Prosperi, Simone Marini. SARITA: a large language model for generating the S1 subunit of the SARS-CoV-2 spike protein
0 -- 0Yajunzi Wang, Jing Li, Haoruo Zha, Shuhe Liu, Daiyun Huang, Lei Fu, Xin Liu. Paradigms, innovations, and biological applications of RNA velocity: a comprehensive review
0 -- 0Zahoor Ahmed, Kiran Shahzadi, Rui Li, Yu-Qing Jiang, Yan-Ting Jin, Muhammad Arif, Juan Feng. An artificial intelligence-based approach for identifying the proteins regulating liquid-liquid phase separation
0 -- 0Max Ward, Mary Richardson, Mihir Metkar. mRNA folding algorithms for structure and codon optimization
0 -- 0Xin Xia, Yajie Zhang, Xiangxiang Zeng, Xing-yi Zhang 0001, Chun-Hou Zheng 0001, Yansen Su. CMOMO: a deep multi-objective optimization framework for constrained molecular multi-property optimization
0 -- 0Yan Sun, Yan Zhao, Junliang Shang, Baojuan Qin, Xiaohan Zhang, Jin-Xing Liu. scRDAN: a robust domain adaptation network for cell type annotation across single-cell RNA sequencing data
0 -- 0Pei Liu, Xiao Liang, Yue Li, Jiawei Luo. ConvNTC: convolutional neural tensor completion for detecting "A-A-B" type biological triplets
0 -- 0Yun Fei Ma, Ye Liu. Intelligent Batch Epitope Identification and Partitioning: an intelligent tool for the identification of B cell dominant epitopes
0 -- 0Qianyi Yan, Xuan Li, Jiangnan Cui, Jianming Rong, Jingsong Zhang, Pingting Gao, Yaochen Xu, Fufang Qiu, Chunman Zuo. Spatial histology and gene-expression representation and generative learning via online self-distillation contrastive learning
0 -- 0Yueyue Wang, Pengrui Teng, Zheyu Wu, Yuna Zhang, Zhisen Shen, Qinhu Zhang, De-Shuang Huang. RGCN-BA: relational graph convolutional network with batch awareness for single-cell RNA sequencing clustering
0 -- 0Si Chun Gu, Thomas Welton, Qiaoyang Sun, Yun-Cheng Wu, Eng-King Tan, Zhi Dong Zhou. The integration of genome-wide and transcriptome-wide association studies in neurodegenerative diseases: opportunities, challenges, and current methodological innovations
0 -- 0Longyi Li, Liyan Dong, Hao Zhang 0064, Dong Xu 0002, Yongli Li. spaLLM: enhancing spatial domain analysis in multi-omics data through large language model integration
0 -- 0Yue Yang, Kairui Guo, Yonggang Zhang 0003, Zhen Fang 0001, Hua Lin, Mark Grosser, Deon Venter, Weihai Lu, Mengjia Wu, Dennis Cordato, Guangquan Zhang 0001, Jie Lu 0001. MetaGeno: a chromosome-wise multi-task genomic framework for ischaemic stroke risk prediction
0 -- 0Thomas Bikias, Evangelos Stamkopoulos, Sai T. Reddy. PLMFit: benchmarking transfer learning with protein language models for protein engineering
0 -- 0Yang Liu, Rongbo Shen, Lu Zhou, Qingyu Xiao, Jiao Yuan, Yixue Li. A data-intelligence-intensive bioinformatics copilot system for large-scale omics research and scientific insights
0 -- 0Chenyu Liu, Qianyi Lu, Jian Li, Di Wang, Zhuoru Wang, Wenli Chen, Yakun Zhang 0003, Caiyu Zhang, Yue Gao 0004, Shangwei Ning. Dynamic changes of synergy relationship between lncRNA and immune checkpoint in cancer progression
0 -- 0Hyejin Yu, Kwanyong Choi, Ji-Yeon Kim, Sunyong Yoo. Multi-level association rule mining and network pharmacology to identify the polypharmacological effects of herbal materials and compounds in traditional medicine
0 -- 0Tung Dang, Artem Lysenko, Keith A. Boroevich, Tatsuhiko Tsunoda. VBayesMM: variational Bayesian neural network to prioritize important relationships of high-dimensional microbiome multiomics data
0 -- 0Qinglu Zhong, Kevin C. Chan, Lei Fu, Ruhong Zhou. A free energy perturbation-assisted machine learning strategy for mimotope screening in neoantigen-based vaccine design

Volume 26, Issue 3

0 -- 0Jun Hu, Yu Zhou, Wen-yi Zhang, Xiao-gen Zhou. RLEAAI: improving antibody-antigen interaction prediction using protein language model and sequence order information
0 -- 0Bingying Luo, Fei Teng, Guo Tang, Weixuan Cen, Xing Liu, Jinmiao Chen, Chi Qu, Xuanzhu Liu, Xin Liu, Wenyan Jiang, Huaqiang Huang, Yu Feng, Xue Zhang, Min Jian, Mei Li, Feng Xi, Guibo Li, Sha Liao, Ao Chen, Weimiao Yu, Xun Xu, Jiajun Zhang. StereoMM: a graph fusion model for integrating spatial transcriptomic data and pathological images
0 -- 0Xin Li, Fan Yang, Yibo Zhang, Zijian Yang, Ruanqi Chen, Meng Zhou 0003, Lin Yang. DeepTFtyper: an interpretable morphology-aware graph neural network for translating histopathology images into molecular subtypes in small cell lung cancer
0 -- 0Yuehua Ou, Qiyi Chen, Ningyu Zhong, Zhihua Du. ProtPhage: a deep learning framework for phage viral protein identification and functional annotation
0 -- 0Fei Ye, Mao Chen, Yixuan Huang, Ruihao Zhang, Xuqi Li, Xiuyuan Wang, Sanyang Han, Lan Ma, Xiao Liu. LightCTL: lightweight contrastive TCR-pMHC specificity learning with context-aware prompt
0 -- 0Zehua Sun, Jing Xu, Yumeng Zhang, Yiwen Zhang, Zhikang Wang, Xiaoyu Wang 0016, Shanshan Li, Yuming Guo 0001, Hsin-Hui Shen, Jiangning Song. Multimodal geometric learning for antimicrobial peptide identification by leveraging alphafold2-predicted structures and surface features
0 -- 0Xichen Liao, Qi Liu, Guohui Chuai. PrimeNet: rational design of Prime editing pegRNAs by deep learning
0 -- 0Kanglin Hsieh, Kai Zhang, Yan Chu, Lishan Yu, Xiaoyang Li, Nuo Hu, Isha Kawosa, Patrick G. Pilié, Pratip K. Bhattacharya, Degui Zhi, Xiaoqian Jiang, Zhongming Zhao, Yulin Dai. iGTP: learning interpretable cellular embedding for inferring biological mechanisms underlying single-cell transcriptomics
0 -- 0Chen Chen, Yong Xu, Jian Ouyang, Xiangyi Xiong, Pawel P. Labaj, Agnieszka Chmielarczyk, Anna Rózanska, Hao Zhang, Keyang Liu, Tieliu Shi, Jun Wu. VirulentHunter: deep learning-based virulence factor predictor illuminates pathogenicity in diverse microbial contexts
0 -- 0Asish Kumar Swain, Rajveer Singh Shekhawat, Pankaj Yadav. ScInfeR: an efficient method for annotating cell types and sub-types in single-cell RNA-seq, ATAC-seq, and spatial omics
0 -- 0Yangyang Wang, Xinyu Yue, Shenghan Lou, Peinan Feng, Binbin Cui, Yanlong Liu. Gene Swin transformer: new deep learning method for colorectal cancer prognosis using transcriptomic data
0 -- 0Yuxin Lin, Zongming Jia, Jixiang Wu, Hubo Yang, Xin Chen, He Wang, Xuedong Wei, Wenying Yan, Xin Qi, Yuhua Huang. Knowledge-guided multi-level network modeling with experimental characterization identifies PRKCA as a novel biomarker and tumor suppressor triggering ferroptosis in prostate cancer
0 -- 0Lauren Theunissen, Thomas Mortier, Yvan Saeys, Willem Waegeman. Evaluation of out-of-distribution detection methods for data shifts in single-cell transcriptomics
0 -- 0Tae-Hyun Kim, Harim Kim, Hyunjin Hwang, Shinwhan Kang, Kijung Shin, Inwha Baek. Gene expression inference based on graph neural networks using L1000 data
0 -- 0Sriniketh Vangaru, Debswapna Bhattacharya. To pack or not to pack: revisiting protein side-chain packing in the post-AlphaFold era
0 -- 0Jing Wang 0057, Junfeng Xia, Dayu Tan, Yunjie Ma, Yansen Su, Chun-Hou Zheng 0001. Multi-view clustering for single-cell RNA-seq data based on graph fusion
0 -- 0Lili Liu, Haixiang Zhang, Yinan Zheng, Tao Gao, Cheng Zheng 0005, Kai Zhang, Lifang Hou, Lei Liu 0004. High-dimensional mediation analysis for longitudinal mediators and survival outcomes
0 -- 0. Correction to: ProtGraph: a tool for the quick and comprehensive exploration and exploitation of the peptide search space derived from protein sequence databases using graphs
0 -- 0Maider Aguerralde-Martin, Mónica Clemente-Císcar, Ana Conesa, Sonia Tarazona. MORE interpretable multi-omic regulatory networks to characterise phenotypes
0 -- 0Sina Majidian, Stephen Hwang, Mohsen Zakeri, Ben Langmead. EvANI benchmarking workflow for evolutionary distance estimation
0 -- 0Alex McSweeney-Davis, Chengran Fang, Emmanuel Caruyer, Anne Kerbrat, Jing-Rebecca Li. Alpha_Mesh_Swc: automatic and robust surface mesh generation from the skeleton description of brain cells
0 -- 0. Editor's Note on 'Bioinformatics in Russia: history and present-day landscape'
0 -- 0Su Xu, Duan Chen, Xue Wang, Shaoyu Li. Robustness and resilience of computational deconvolution methods for bulk RNA sequencing data
0 -- 0Runtian Gao, Heng Hu, Zhongjun Jiang, Shuqi Cao, Guohua Wang, Yuming Zhao, Tao Jiang 0021. SVHunter: long-read-based structural variation detection through the transformer model
0 -- 0Tianhao Li, Zixuan Wang, Yuhang Liu, Sihan He, Quan Zou 0001, Yongqing Zhang. An overview of computational methods in single-cell transcriptomic cell type annotation
0 -- 0Jingchen Zhai, Xiguang Qi, Lianjin Cai, Yue Liu, Haocheng Tang, Lei Xie, Junmei Wang. NNKcat: deep neural network to predict catalytic constants (Kcat) by integrating protein sequence and substrate structure with enhanced data imbalance handling
0 -- 0Suresh Pokharel, Kepha Barasa, Pawel Pratyush, Dukka B. Kc. PLM-DBPs: enhancing plant DNA-binding protein prediction by integrating sequence-based and structure-aware protein language models
0 -- 0Xiaoyan Yu, Yixuan Ren, Min Xia, Zhenqiu Shu, Liehuang Zhu. Decoupled GNNs based on multi-view contrastive learning for scRNA-seq data clustering
0 -- 0Xun Wang 0010, Tongyu Han, Runqiu Feng, Zhijun Xia, Hanyu Wang, Wenqian Yu, Huanhuan Dai, Haonan Song, Tao Song 0001. GTE-PPIS: a protein-protein interaction site predictor based on graph transformer and equivariant graph neural network
0 -- 0Himansu Kumar, Zikang Chen, Abayomi Adegunlehin, Loren Trowbridge, Leonardo Aguilar, Pora Kim. KinaseFusionDB: an integrative knowledge of kinase fusion proteins in multi-scales
0 -- 0Li Huang, Weikang Gong, Dongsheng Chen. scValue: value-based subsampling of large-scale single-cell transcriptomic data for machine and deep learning tasks
0 -- 0Jingjing Wang, Yanpeng Zhao, Zhijiang Yang, Ge Yao, Penggang Han, Jiajia Liu, Chang Chen, Peng Zan, Xiukun Wan, Xiaochen Bo, Hui Jiang. IECata: interpretable bilinear attention network and evidential deep learning improve the catalytic efficiency prediction of enzymes
0 -- 0Maren Hackenberg, Laia Canal Guitart, Rolf Backofen, Harald Binder. Evaluating discrepancies in dimensionality reduction for time-series single-cell RNA-sequencing data
0 -- 0Jianwei Huang, Youli Zhang, Shulin Ren, Ziyang Wang, Xiaocheng Jin, Xiaoli Lu, Yu Zhang, Xiaoping Min, Shengxiang Ge, Jun Zhang, Ningshao Xia. MambaPhase: deep learning for liquid-liquid phase separation protein classification
0 -- 0Fulan Deng, Jiawei Zou, Miaochen Wang, Yida Gu, Jiale Wu, Lianchong Gao, Yuan Ji, Henry H. Y. Tong, Jie Chen, Wantao Chen, Lianjiang Tan, Yaoqing Chu, Xin Zou, Jie Hao. DECEPTICON: a correlation-based strategy for RNA-seq deconvolution inspired by a variation of the Anna Karenina principle
0 -- 0Hao Tang, Feng Jiang, Zhi Zhang, Jiaojiao Yang, Lu Li, Qingye Zhang. Metabolism-associated protein network constructing and host-directed anti-influenza drug repurposing
0 -- 0Rhys Gillman, Matt A. Field, Ulf Schmitz, Lionel Hebbard. TARGET-SL: precision essential gene prediction using driver prioritisation and synthetic lethality
0 -- 0Mingxuan Zhang, Yinglei Lai. An order-preserving batch-effect correction method based on a monotonic deep learning framework
0 -- 0Zequn Zhang, Huijun Li, Yuxi Chen, Xiaoli Li, Dongqing Wei, Hongyan Wu. HGCMLDA: predicting lncRNA-disease associations using hypergraph contrastive learning and multi-scale attentional feature fusion
0 -- 0Shangwei Guo, Shengming Zhou, Guohua Wang, Fang Wang. SCPline: An interactive framework for the single-cell proteomics data preprocessing
0 -- 0Jing Yang, Minggui Song, Yifan Bu, Haonan Zhao, Chenghui Liu, Ting Zhang, Chujun Zhang, Shutu Xu, Chuang Ma. Machine learning-augmented m6A-Seq analysis without a reference genome
0 -- 0Saiyam Jogani, Anand Santosh Pol, Mayur Prajapati, Amit Samal, Kriti Bhatia, Jayendra Parmar, Urvik Patel, Falak Shah, Nisarg Vyas, Saurabh Gupta. scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery
0 -- 0Sunghong Park, Dong-Gi Lee, Juhyeon Kim, Seung Ho Kim, Hyeon Jin Hwang, Hyunjung Shin, Hyun Goo Woo. PPIxGPN: plasma proteomic profiling of neurodegenerative biomarkers with protein-protein interaction-based eXplainable graph propagational network
0 -- 0Mofan Feng, Liangjie Liu, Zhuo-Ning Xian, Xiaoxi Wei, Keyi Li, Wenqian Yan, Qing Lu, Yi Shi, Guang He. PSTP: accurate residue-level phase separation prediction using protein conformational and language model embeddings
0 -- 0Abrar Rahman Abir, Md Toki Tahmid, Rafiqul Islam Rayan, M. Saifur Rahman. DeepRNA-Twist: language-model-guided RNA torsion angle prediction with attention-inception network
0 -- 0Yijie He, Yaqin Tang, Pengcheng Tan, Dongyu Huang, Yongheng Wang, Tong Wen, Lin Huang, Jia Wang, Lizhen Shao, Qinyu Cai, Zhimou Li, Yueyang Wang, Taihang Liu, Zhijie Han. Genetic regulation of lncRNA expression in whole human brain and their contribution to CNS disorders
0 -- 0Jing Li, Jia Mi, Wei Lin, Fengjuan Tian, Jing Wan, Jingyang Gao, Yigang Tong. VirNucPro: an identifier for the identification of viral short sequences using six-frame translation and large language models
0 -- 0Mikhail S. Gelfand. On "Bioinformatics in Russia: history and present-day landscape" by M.A. Nawaz, I.E. Pamirsky, and K.S. Golokhvast
0 -- 0Li-Mei Qian, Shi-Xiang Wang, Wen Zhou, Zi-Xin Qin, Ying-nan Wang, Qi Zhao, Rui-Hua Xu. Individualized metagenomic network model for colorectal cancer diagnosis: insights into viral regulation of gut microecology
0 -- 0Lis Arend, Klaudia Adamowicz, Johannes R. Schmidt, Yuliya Burankova, Olga I. Zolotareva, Olga Tsoy, Josch Konstantin Pauling, Stefan Kalkhof, Jan Baumbach, Markus List, Tanja Laske. Systematic evaluation of normalization approaches in tandem mass tag and label-free protein quantification data using PRONE
0 -- 0Hailong Yang, Jia Wang, Wenyan Wang, Shufang Shi, Lijing Liu, Yuhua Yao, Geng Tian, Peizhen Wang, Jialiang Yang. MMsurv: a multimodal multi-instance multi-cancer survival prediction model integrating pathological images, clinical information, and sequencing data
0 -- 0Xianglin Zhang, Wei Zhang 0241, Jinyi Zhang, Xiuhong Lyu, Haoran Pan, Tianwei Jia, Ting Wang, Xiaowo Wang, Haiyang Guo. Simulation-guided pan-cancer analysis identifies a novel regulator of CpG island hypermethylation heterogeneity
0 -- 0Yuhuan Liu, Xueying Wang, Haitian Zhong, Jixiu Zhai, Xiaojuan Gong, Tianchi Lu. PhosF3C: a feature fusion architecture with fine-tuned protein language model and conformer for prediction of general phosphorylation site
0 -- 0Anas Bilal, Muhammad Taseer Suleman, Khalid Almohammadi, Abdulkareem Alzahrani, Xiaowen Liu. O-methylation sites in ribonucleic acid using diverse classifiers
0 -- 0Keisuke Yamada, Kanta Suga, Naoko Abe, Koji Hashimoto, Susumu Tsutsumi, Masahito Inagaki, Fumitaka Hashiya, Hiroshi Abe, Michiaki Hamada. Multi-objective computational optimization of human 5′ UTR sequences
0 -- 0. Correction to: DOMSCNet: a deep learning model for the classification of stomach cancer using multi-layer omics data
0 -- 0Yuting Hu, Feng Hu, Hongwen Zhang 0008, Hongling Xu, Jixiang Gao, Wenshuai Deng, Zijing Tian, Qiaoyu Hu, Honglin Li 0003, Yanyan Diao. RPSubAlign: a novel sequence-based molecular representation method for retrosynthesis prediction with improved validity and robustness
0 -- 0Tung Dang, Yushiro Fuji, Kie Kumaishi, Erika Usui, Shungo Kobori, Takumi Sato, Megumi Narukawa, Yusuke Toda, Kengo Sakurai, Yuji Yamasaki, Hisashi Tsujimoto, Masami Yokota Hirai, Yasunori Ichihashi, Hiroyoshi Iwata. I-SVVS: integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data
0 -- 0Osafu Augustine Egbon, John W. Hickey, Benedict Anchang. Fusion of spatiotemporal and network models to prioritize multiscale effects in single-cell perturbations
0 -- 0Ana Stolnicu, Nensi Ikonomi, Peter Eckhardt-Bellmann, Johann M. Kraus, Hans A. Kestler. Robust signalling entropy estimation for biological process characterisation
0 -- 0Alvira Ajadee, Sabkat Mahmud, Md. Ahad Ali, Md. Manir Hossain Mollah, Reaz Ahmmed, Md. Nurul Haque Mollah. In-silico discovery of type-2 diabetes-causing host key genes that are associated with the complexity of monkeypox and repurposing common drugs
0 -- 0Luxuan Wang, Beihong Ji, Jingchen Zhai, Junmei Wang. Advancing promiscuous aggregating inhibitor analysis with intelligent machine learning classification
0 -- 0Hong-Qi Zhang, Xin-Ran Lin, Yan-Ting Wang, Wen-Fang Pei, Guang-Ji Ma, Ze-Xu Zhou, Ke-Jun Deng, Dan Yan, Tian-Yuan Liu. EDS-Kcr: deep supervision based on large language model for identifying protein lysine crotonylation sites across multiple species
0 -- 0Xiao Ding, Yun Ma, Shicheng Li, Jingze Liu, Luyao Qin, Aiping Wu. Influenza virus reassortment patterns exhibit preference and continuity while uncovering cross-species transmission events
0 -- 0Zhiwei Cheng, Yongyong Ren, Xinbo Wang, Yuening Zhang, Yingqi Hua, Hongyu Zhao 0003, Hui Lu 0004. A novel prognostic framework for HBV-infected hepatocellular carcinoma: insights from ferroptosis and iron metabolism proteomics
0 -- 0Ning Wang, Minghui Wu, Wenchao Gu, Chenglong Dai, Zongru Shao, K. P. Subbalakshmi. MSFT-transformer: a multistage fusion tabular transformer for disease prediction using metagenomic data
0 -- 0Xudong Liu, Zhiwei Nie, Haorui Si, Xurui Shen, Yutian Liu 0004, Xiansong Huang, Tianyi Dong, Fan Xu, Zhixiang Ren, Peng Zhou, Jie Chen 0001. in silico virus evolution
0 -- 0Xianjun Han, Zhenglong Zhang, Can Bai, Zijian Wu. Integrated multimodal hierarchical fusion and meta-learning for enhanced molecular property prediction
0 -- 0Liye Chen, Biaoshun Li, Yihao Chen, MuJie Lin, Shipeng Zhang, Chenxin Li, Yu Pang, Ling Wang. ADCNet: a unified framework for predicting the activity of antibody-drug conjugates
0 -- 0Muhammad A Nawaz, Igor E. Pamirsky, Kirill S. Golokhvast. Response to letter to editor "On 'Bioinformatics in Russia: history and present-day landscape' by M.A. Nawaz, I.E. Pamirsky, and K.S. Golokhvast" by Mikhail Gelfand
0 -- 0Jiahui Guan, Lantian Yao, Peilin Xie, Zhihao Zhao, Dian Meng, Tzong-Yi Lee, Junwen Wang, Ying-Chih Chiang. Graph-RPI: predicting RNA-protein interactions via graph autoencoder and self-supervised learning strategies
0 -- 0Fangyu Mo, Qinghong Qian, Xiaolin Lu, Dihuai Zheng, Wenjie Cai, Jie Yao, Hongyu Chen, Yujie Huang, Xiang Zhang, Sanling Wu, Yifei Shen, Yinqi Bai, Yongcheng Wang, Weiqin Jiang, Longjiang Fan. K-mer embedding of microbiomic single-microbe RNA sequencing data
0 -- 0Kaizhuang Jing, Tingchu Wei, Xuedie Gu, Guoliang Lin, Lin Liu, Jing Luo. Deep learning reveals determinants of transcriptional infidelity at nucleotide resolution in the allopolyploid line by goldfish and common carp hybrids
0 -- 0Liangcan Li, Xin Li, Hao Wu. A novel deep learning framework with dynamic tokenization for identifying chromatin interactions along with motif importance investigation
0 -- 0Peidong Zhang, Xingang Peng, Rong Han, Ting Chen 0006, Jianzhu Ma. Rag2Mol: structure-based drug design based on retrieval augmented generation
0 -- 0Yuanyuan Zeng, Zhiyu You, Jiayang Guo, Jialin Zhao 0005, Ying Zhou, Jialiang Huang, Xiaowen Lyu, Longbiao Chen, Qiyuan Li. Chrombus-XMBD: a graph convolution model predicting 3D-genome from chromatin features
0 -- 0Mike van Santvoort, Federica Eduati. An algorithmic perspective on deciphering cell-cell interactions with spatial omics data
0 -- 0Pi-Jing Wei, Huaiwan Jin, Zhen Gao, Yansen Su, Chun-Hou Zheng 0001. GAEDGRN: reconstruction of gene regulatory networks based on gravity-inspired graph autoencoders
0 -- 0Chen Yang, Yingqi Zhao, Boyuan Xue, Shaojie Wang, Haijia Su. Escherichia coli microbial consortia
0 -- 0Rym Bouriga, Caroline Bailleux, Jocelyn Gal, Emmanuel Chamorey, Baharia Mograbi, Jean-Michel Hannoun-Levi, Gérard Milano. Advances and critical aspects in cancer treatment development using digital twins
0 -- 0Fengyi Guo, Yuanbo Li, Hongyuan Zhao, Xiaogang Liu, Jian Mao, Dongna Ma, Shuangping Liu. GKNnet: an relational graph convolutional network-based method with knowledge-augmented activation layer for microbial structural variation detection
0 -- 0Zhixia Teng, Zhaowen Tian, Murong Zhou, Guohua Wang, Zhen Tian, Yuming Zhao. Enhancing LncRNA-miRNA interaction prediction with multimodal contrastive representation learning
0 -- 0. Correction to: ScInfeR: an efficient method for annotating cell types and sub-types in single-cell RNA-seq, ATAC-seq, and spatial omics
0 -- 0Mingjuan Wang, Xuetong Chen, Mingxing Liu, Huiying Luo, Shuangshuang Zhang, Jie Guo, Jinghui Wang, Li Zhou, Na Zhang, Hongyan Li, Chao Wang, Liang Li, Zhenzhong Wang, Haiqing Wang, Zihu Guo, Yan Li 0025, Yonghua Wang. Decoding herbal combination models through systematic strategies: insights from target information and traditional Chinese medicine clinical theory
0 -- 0Giulia Cesaro, James Shiniti Nagai, Nicolò Gnoato, Alice Chiodi, Gaia Tussardi, Vanessa Klöker, Carmelo Vittorio Musumarra, Ettore Mosca, Ivan G. Costa, Barbara Di Camillo, Enrica Calura, Giacomo Baruzzo. Advances and challenges in cell-cell communication inference: a comprehensive review of tools, resources, and future directions
0 -- 0Alain J. Mbebi, Facundo Mercado, David Hobby, Hao Tong, Zoran Nikoloski. Advances in multi-trait genomic prediction approaches: classification, comparative analysis, and perspectives
0 -- 0Kun Wu, Zixu Wang, Xiulong Yang, Yangyang Chen 0006, Fulvio Mastrogiovanni, Jialu Zhang, Lizhuang Liu. TransMA: an explainable multi-modal deep learning model for predicting properties of ionizable lipid nanoparticles in mRNA delivery
0 -- 0Murong Zhou, Zeyu Luo, Yu-Hang Yin, Qiaoming Liu, Guohua Wang, Yuming Zhao. scATD: a high-throughput and interpretable framework for single-cell cancer drug resistance prediction and biomarker identification
0 -- 0Xuchao Zhang, Jing Chen, Yongtian Wang, Xiaofeng Wang, Jialu Hu, Jiajie Peng, Xuequn Shang 0001, Yanpu Wang, Tao Wang 0082. cfMethylPre: deep transfer learning enhances cancer detection based on circulating cell-free DNA methylation profiling
0 -- 0Xin Gao, Hanqun Cao, Jinpeng Li 0004, Jiezhong Qiu, Guangyong Chen, Pheng-Ann Heng. Gated-GPS: enhancing protein-protein interaction site prediction with scalable learning and imbalance-aware optimization
0 -- 0Guliang Wang, Ioannis Mouratidis, Kimonas Provatas, Nikol Chantzi, Michail Patsakis, Ilias Georgakopoulos-Soares, Karen M. Vasquez. ZSeeker: an optimized algorithm for Z-DNA detection in genomic sequences
0 -- 0Rui Zhang, Huaming Wu. GC-balanced polar codes correcting insertions, deletions and substitutions for DNA storage
0 -- 0Sara H. Mohamed, Mohamed Hamed, Hussain A Alamoudi, Zayd Jastaniah, Fadhl M. Al-Akwaa, Asmaa Reda. Helicobacter pylori-associated gastric cancer identifies hub genes as a novel therapeutic biomarker
0 -- 0Yu Shi, Wei Xu, Pingzhao Hu. Out of distribution learning in bioinformatics: advancements and challenges
0 -- 0Wenbo Guo, Zeyu Chen, Jin Gu. Computational modeling of single-cell dynamics data
0 -- 0Hongqiang Lyu, Pei Cao, Wenyao Long, Xiaoran Yin, Shengjun Xu, Laiyi Fu. DeepExDC interprets genomic compartmentalization changes in single-cell Hi-C data
0 -- 0Feifei Xia, Max A. Verbiest, Oxana Lundström, Tugce Bilgin Sonay, Michael Baudis, Maria Anisimova. Multicancer analyses of short tandem repeat variations reveal shared gene regulatory mechanisms
0 -- 0Tianjiao Zhang, Saihong Shao, Hongfei Zhang, Zhongqian Zhao, Xingjie Zhao, Zhao-Xiang Zhang 0001, Zhenxing Wang, Guohua Wang. KansformerEPI: a deep learning framework integrating KAN and transformer for predicting enhancer-promoter interactions
0 -- 0Jelard Aquino, Daniel Witoslawski, Steve Park, Jessica Holder, Amei Amei, Mira V. Han. A novel splicing graph allows a direct comparison between exon-based and splice junction-based approaches to alternative splicing detection
0 -- 0Zhiyue Tom Hu, Yaodong Yu, Ruoqiao Chen, Shan-Ju Yeh, Bin Chen, Haiyan Huang. Large-scale information retrieval and correction of noisy pharmacogenomic datasets through residual thresholded deep matrix factorization
0 -- 0Hao Mei, Zhiyuan Wang, Hang Yang, Xiaoke Li, Yaqing Xu. Network analysis of multivariate time series data in biological systems: methods and applications
0 -- 0Partha Pratim Ray. Should LLMs be over empowered for high-stake regulatory research?
0 -- 0Ting Li, Henghui Fan, Jianping Zhao 0001, Xiaomei Yang, Junfeng Xia. MultiPep-DLCL: recognition of multifunctional therapeutic peptides through deep learning with label-sequence contrastive learning
0 -- 0. Correction to: Bioinformatics in Russia: history and present-day landscape
0 -- 0Yan Zhao, Huaiyu Wang. Artificial intelligence-driven circRNA vaccine development: multimodal collaborative optimization and a new paradigm for biomedical applications
0 -- 0Yihe Yang, Noah Lorincz-Comi, Mengxuan Li, Xiaofeng Zhu. cis-Mendelian randomization method robust to weak instrument bias and horizontal pleiotropy bias
0 -- 0Ruilin Su, Binyang Huang, Junyan Tan, Zhencai Shen, Ping Zhong 0003, Jianfeng Liu. Mutual information stacking method for prediction of the growth traits in pigs
0 -- 0Cheng Zhu, Sen Cao, Tianfeng Shang, Jingjing Guo, An Su, Chengxi Li, Hongliang Duan. Predicting the structures of cyclic peptides containing unnatural amino acids by HighFold2
0 -- 0Xinyi Tang, Ran Liu. De-motif sampling: an approach to decompose hierarchical motifs with applications in T cell recognition
0 -- 0Xiang Lian, Xia Kuang, Dong-Dong Zhang, Qian Xu, Anqiang Ye, Cheng-Yu Wang, Hong-Tu Cui, Hai-Xia Guo, Ji-Yun Zhang, Yuan Liu, Ge-Fei Hao, Zhenshun Cheng, Feng-Biao Guo. Systematic identification of cancer-type-specific drugs based on essential genes and validations in lung adenocarcinoma
0 -- 0Lianchong Gao, Yujun Liu, Jiawei Zou, Fulan Deng, Zheqi Liu, Zhen Zhang, Xinran Zhao, Lei Chen, Henry H. Y. Tong, Yuan Ji, Huangying Le, Xin Zou, Jie Hao. Deep scSTAR: leveraging deep learning for the extraction and enhancement of phenotype-associated features from single-cell RNA sequencing and spatial transcriptomics data
0 -- 0Yu Cheng, Xinjia Ruan, Xiaofan Lu, YuQing Yang, Yuhang Wang, Shangjin Yan, Yuzhe Sun, Fangrong Yan, Liyun Jiang, Tiantian Liu. Accounting for the impact of rare variants on causal inference with RARE: a novel multivariable Mendelian randomization method
0 -- 0Hongyu Zhang, Weining Li, Jinting Guan. scTsI: an effective two-stage imputation method for single-cell RNA-seq data

Volume 26, Issue 2

0 -- 0Emily C. Hector, Daiwei Zhang, Leqi Tian, Junning Feng, Xianyong Yin, Tianyi Xu, Markku Laakso, Yun Bai, Jiashun Xiao, Jian Kang 0003, Tianwei Yu. Dissecting genetic regulation of metabolic coordination
0 -- 0Mira Koul, Shalini Kaushik, Kavya Singh, Deepak Sharma. VITALdb: to select the best viroinformatics tools for a desired virus or application
0 -- 0Jie Ni, Bin Li, Shumei Miao, Xinting Zhang, Donghui Yan, Shengqi Jing, Shan Lu, Zhuoying Xie, Xin Zhang, Yun Liu. MethPriorGCN: a deep learning tool for inferring DNA methylation prior knowledge and guiding personalized medicine
0 -- 0Gefei Zhao, Binbin Lai. SC-VAR: a computational tool for interpreting polygenic disease risks using single-cell epigenomic data
0 -- 0Carolina Monzó, Maider Aguerralde-Martin, Carlos Martínez-Mira, Angeles Arzalluz-Luque, Ana Conesa, Sonia Tarazona. MOSim: bulk and single-cell multilayer regulatory network simulator
0 -- 0Bingqing Han, Yipeng Zhang, Longlong Li, Xinqi Gong, Kelin Xia. TopoQA: a topological deep learning-based approach for protein complex structure interface quality assessment
0 -- 0Yixuan Jin, Juanjuan Huang, Xu Sun, Yabo Fang, Jiageng Wu, Jianshi Du, Jiwei Jia, Guoqing Wang. GiGs: graph-based integrated Gaussian kernel similarity for virus-drug association prediction
0 -- 0Pengfei Zhu, Han Shu, Yongtian Wang, Xiaofeng Wang, Yuan Zhao, Jialu Hu, Jiajie Peng, Xuequn Shang 0001, Zhen Tian, Jing Chen, Tao Wang 0082. MAEST: accurately spatial domain detection in spatial transcriptomics with graph masked autoencoder
0 -- 0Jilong Bian, Hao Lu, Limin Wei, Yang Li 0130, Guohua Wang. Relational similarity-based graph contrastive learning for DTI prediction
0 -- 0. Correction to: STMGraph: spatial-context-aware of transcriptomes via a dual-remasked dynamic graph attention model
0 -- 0Duc Hai Nguyen, Woong-Ki Kim. Disrupted microbial cross-feeding and altered L-phenylalanine consumption in people living with HIV
0 -- 0Yahao Wu, Jing Liu, Yanni Xiao, Shuqin Zhang, Limin Li. CoupleVAE: coupled variational autoencoders for predicting perturbational single-cell RNA sequencing data
0 -- 0Maria Llambrich, Frans M. van der Kloet, Lluc Sementé, Anaïs Rodrigues, Saer Samanipour, Pierre-Hugues Stefanuto, Johan A. Westerhuis, Raquel Cumeras, Jesús Brezmes. GcDUO: an open-source software for GC × GC-MS data analysis
0 -- 0Yijun Mao, Jiale Wu, Jian Weng 0001, Ming Li 0049, Yunyan Xiong, Wanrong Gu, Rongjin Jiang, Rui Pang, Xudong Lin, Deyu Tang. Inter-view contrastive learning and miRNA fusion for lncRNA-protein interaction prediction in heterogeneous graphs
0 -- 0Haolong Zeng, Chaoyi Yin, Chunyang Chai, Yuezhu Wang, Qi Dai, Huiyan Sun. Cancer gene identification through integrating causal prompting large language model with omics data-driven causal inference
0 -- 0Xusheng Ai, Melissa C. Smith, F. Alex Feltus. GEMDiff: a diffusion workflow bridges between normal and tumor gene expression states: a breast cancer case study
0 -- 0Zhen Gao, Yansen Su, Jin Tang 0001, Huaiwan Jin, Yun Ding, Rui-Fen Cao, Pi-Jing Wei, Chun-Hou Zheng 0001. AttentionGRN: a functional and directed graph transformer for gene regulatory network reconstruction from scRNA-seq data
0 -- 0Mingfei Han 0001, Xiaoqing Chen, Xiao Li, Jie Ma, Tao Chen 0005, Chunyuan Yang, Juan Wang, Yingxing Li, Wenting Guo, Yunping Zhu. MulNet: a scalable framework for reconstructing intra- and intercellular signaling networks from bulk and single-cell RNA-seq data
0 -- 0Elise Jorge, Sylvain Foissac, Pierre Neuvial, Matthias Zytnicki, Nathalie Vialaneix. A comprehensive review and benchmark of differential analysis tools for Hi-C data
0 -- 0Oleksandr Narykov, Yitan Zhu, Thomas S. Brettin, Yvonne A. Evrard, Alexander Partin, Fangfang Xia, Maulik Shukla, Priyanka Vasanthakumari, James H. Doroshow, Rick L. Stevens. Data imbalance in drug response prediction: multi-objective optimization approach in deep learning setting
0 -- 0Kasmika Borah, Himanish Shekhar Das, Ram Kaji Budhathoki, Khursheed Aurangzeb, Saurav Mallik. DOMSCNet: a deep learning model for the classification of stomach cancer using multi-layer omics data
0 -- 0Saleh Sereshki, Stefano Lonardi. Predicting differentially methylated cytosines in TET and DNMT3 knockout mutants via a large language model
0 -- 0Adriano Fonzino, Pietro Luca Mazzacuva, Adam Handen, Domenico Alessandro Silvestris, Annette Arnold, Riccardo Pecori, Graziano Pesole, Ernesto Picardi. REDInet: a temporal convolutional network-based classifier for A-to-I RNA editing detection harnessing million known events
0 -- 0Xuexin Chen, Ruichu Cai, Zhengting Huang, Zijian Li 0001, Jie Zheng 0002, Min Wu 0008. Interpretable high-order knowledge graph neural network for predicting synthetic lethality in human cancers
0 -- 0Riikka Huusari, Tianduanyi Wang, Sándor Szedmák, Diogo Dias, Tero Aittokallio, Juho Rousu. Scaling up drug combination surface prediction
0 -- 0Wei Xu, Gang Luo, Weiyu Meng, Xiaobing Zhai, Keli Zheng, Ji Wu, Yanrong Li, Abao Xing, Junrong Li, Zhifan Li, Ke Zheng, Kefeng Li. MRAgent: an LLM-based automated agent for causal knowledge discovery in disease via Mendelian randomization
0 -- 0Hanwen Zhang, Deng Xiong, Xianggen Liu, Jiancheng Lv 0001. MolEM: a unified generative framework for molecular graphs and sequential orders
0 -- 0Ruijun Mao, Li Wan, MingHao Zhou, Dongxi Li. Cox-Sage: enhancing Cox proportional hazards model with interpretable graph neural networks for cancer prognosis
0 -- 0Xuwen Wang, Zhili Chang, Yuqian Liu, Shenjie Wang, Xiaoyan Zhu 0003, Yang Shao, Jiayin Wang. EMcnv: enhancing CNV detection performance through ensemble strategies with heterogeneous meta-graph neural networks
0 -- 0Oleksandr Cherednichenko, Maria S. Poptsova. Kolmogorov-Arnold networks for genomic tasks
0 -- 0Hailin Chen, Kuan Chen. Ensemble learning based on matrix completion improves microbe-disease association prediction
0 -- 0Sijie Li, Heyang Hua, Shengquan Chen. Graph neural networks for single-cell omics data: a review of approaches and applications
0 -- 0Bo Li 0002, Yongkang Zhao, Jing Hu 0003, Shihua Zhang, Xiaolong Zhang 0002. scSAMAC: saliency-adjusted masking induced attention contrastive learning for single-cell clustering
0 -- 0Qi Dong, Yingying Guo, Chen Lv, Lingxue Ren, Bo Chen, Yan Wang, Yang Liu, Mingyue Liu, Kaidong Liu, Nan Zhang, Linzhu Wang, Shaocong Sang, Xin Li, Yang Hui, Haihai Liang, Yunyan Gu. Unveiling a novel cancer hallmark by evaluation of neural infiltration in cancer
0 -- 0Xiaoyan Zhou, Luca Parisi, Wentao Huang, Yihan Zhang, Xiaoqun Huang, Mansour Youseffi, Farideh Javid, Renfei Ma. A novel integrative multimodal classifier to enhance the diagnosis of Parkinson's disease
0 -- 0Jinmiao Song, Yatong Hao, Shuang Zhao, Peng Zhang, Qilin Feng, Qiguo Dai, Xiaodong Duan. Dual-stream cross-modal fusion alignment network for survival analysis
0 -- 0Shifu Luo, Hui Peng, Ying Shi 0004, Jiaxin Cai, Songming Zhang 0002, Ningyi Shao, Jinyan Li. Integration of proteomics profiling data to facilitate discovery of cancer neoantigens: a survey
0 -- 0Jing Zou, Wenyi Zhang, Jun Hu, Xiaogen Zhou, Biao Zhang. DockEM: an enhanced method for atomic-scale protein-ligand docking refinement leveraging low-to-medium resolution cryo-EM density maps
0 -- 0Yuguang Li, Zhen Tian, Xiaofei Nan, Shoutao Zhang, Qinglei Zhou, Shuai Lu. HSSPPI: hierarchical and spatial-sequential modeling for PPIs prediction
0 -- 0Sizhe Qiu, Bozhen Hu, Jing Zhao, Weiren Xu, Aidong Yang. Seq2Topt: a sequence-based deep learning predictor of enzyme optimal temperature
0 -- 0Himansu Kumar, Abayomi Adegunlehin, Zikang Chen, Pora Kim. FusionPub, a therapeutic landscape of human fusion genes
0 -- 0Qi Ge, Rui Qin, Shuang Liu, Quan Guo, Changcai Han, Weigang Chen. Pragmatic soft-decision data readout of encoded large DNA
0 -- 0Jean-Pierre Borg, Jacques Colinge, Patrice Ravel. Testing and overcoming the limitations of modular response analysis
0 -- 0Jair Herazo-Álvarez, Marco Mora, Sara Cuadros-Orellana, Karina Vilches-Ponce, Ruber Hernández-García. A review of neural networks for metagenomic binning
0 -- 0Qiufeng Chen, Lijun Quan, Lexin Cao, Bei Zhang, Zhijun Zhang, Liangchen Peng, Junkai Wang, Yelu Jiang, Liangpeng Nie, Geng Li, Tingfang Wu, Qiang Lyu. DS-MVP: identifying disease-specific pathogenicity of missense variants by pre-training representation
0 -- 0Yichong Li, Xiaoyong Pan, Hongbin Shen, Yang Yang 0030. DRAG: design RNAs as hierarchical graphs with reinforcement learning
0 -- 0Nicolaas F. V. Burger, Vittorio F. Nicolis, Anna-Maria Botha. Evaluating long-read assemblers to assemble several aphididae genomes
0 -- 0Zhimin Li, Wenlan Chen, Hai Zhong, Cheng Liang 0001. PCLSurv: a prototypical contrastive learning-based multi-omics data integration model for cancer survival prediction
0 -- 0Nathaniel S. O'Connell, Byron C. Jaeger, Garrett S. Bullock, Jaime Lynn Speiser. A comparison of random forest variable selection methods for regression modeling of continuous outcomes
0 -- 0Jiashan Li, Xi Chen, He Huang, Mingliang Zeng, Jingcheng Yu, Xinqi Gong, Qiwei Ye. $\mathcal{S}$ able: bridging the gap in protein structure understanding with an empowering and versatile pre-training paradigm
0 -- 0Peng Zhou, Zixiu Li, Feifan Liu, Euijin Kwon, Tien-Chan Hsieh, Shangyuan Ye, Shobha Vasudevan, Jung Ae Lee, Khanh-Van Tran, Chan Zhou. BAMBI integrates biostatistical and artificial intelligence methods to improve RNA biomarker discovery
0 -- 0Laszlo Dobson, Gábor E. Tusnády, Peter Tompa. Regularly updated benchmark sets for statistically correct evaluations of AlphaFold applications
0 -- 0Meng Yuan, Seppe Goovaerts, Myoung K. Lee, Jay Devine, Stephen Richmond, Susan Walsh, Mark D. Shriver, John R. Shaffer, Mary L. Marazita, Hilde Peeters, Seth M. Weinberg, Peter Claes. Optimized phenotyping of complex morphological traits: enhancing discovery of common and rare genetic variants
0 -- 0Liang Chen, Madison Dautle, Ruoying Gao, Shaoqiang Zhang, Yong Chen. Inferring gene regulatory networks from time-series scRNA-seq data via GRANGER causal recurrent autoencoders
0 -- 0Shuang Ge, Shuqing Sun, Huan Xu, Qiang Cheng, Zhixiang Ren. Deep learning in single-cell and spatial transcriptomics data analysis: advances and challenges from a data science perspective
0 -- 0Shrabanti Chowdhury, Sammy Ferri-Borgogno, Peng Yang, Wenyi Wang, Jie Peng, Samuel C. Mok, Pei Wang. Learning directed acyclic graphs for ligands and receptors based on spatially resolved transcriptomic data of ovarian cancer
0 -- 0Wenhan Guo, Yuan Gao, Dan Du, Jason E. Sanchez, Yupeng Li, Weihong Qiu, Lin Li. Elucidating the interactions between Kinesin-5/BimC and the microtubule: insights from TIRF microscopy and molecular dynamics simulations
0 -- 0Yongfei Hu, Xinyu Li, Ying Yi, Yan Huang, Guangyu Wang, Dong Wang 0011. Deep learning-driven survival prediction in pan-cancer studies by integrating multimodal histology-genomic data
0 -- 0De-Min Liang, Pu-Feng Du. scMUG: deep clustering analysis of single-cell RNA-seq data on multiple gene functional modules
0 -- 0Abir Omran, Alexander Amberg, Gerhard F. Ecker. Exploring diverse approaches for predicting interferon-gamma release: utilizing MHC class II and peptide sequences
0 -- 0Minfang Song, Shuai Ma, Gong Wang, Yukun Wang, Zhenzhen Yang, Bin Xie, Tongkun Guo, Xingxu Huang, Liye Zhang. Benchmarking copy number aberrations inference tools using single-cell multi-omics datasets
0 -- 0Alessandra Aldieri, Thiranja Prasad Babarenda Gamage, Antonino Amedeo La Mattina, Axel Loewe, Francesco Pappalardo 0001, Marco Viceconti. Consensus statement on the credibility assessment of machine learning predictors
0 -- 0Annette Spooner, Mohammad Karimi Moridani, Barbra Toplis, Jason Behary, Azadeh Safarchi, Salim Maher, Fatemeh Vafaee, Amany Zekry, Arcot Sowmya. Benchmarking ensemble machine learning algorithms for multi-class, multi-omics data integration in clinical outcome prediction
0 -- 0Yunhui Qi, Xinyi Wang, Li-Xuan Qin. Optimizing sample size for supervised machine learning with bulk transcriptomic sequencing: a learning curve approach
0 -- 0Xiaoyan Wang, Junwei Luo, Lili Wu, HuiMin Luo, Fei Guo. deepTAD: an approach for identifying topologically associated domains based on convolutional neural network and transformer model

Volume 26, Issue 1

0 -- 0Sergio-Llaneza Lago, William D. Fraser, Darrell Green. Bayesian unsupervised clustering identifies clinically relevant osteosarcoma subtypes
0 -- 0Lingpeng Kong, Hong Cheng, Kun Zhu, Bo Song. LOGOWheat: deep learning-based prediction of regulatory effects for noncoding variants in wheats
0 -- 0Junwei Luo, Jiaojiao Wang, Jingjing Wei, Chaokun Yan, HuiMin Luo. DeepHapNet: a haplotype assembly method based on RetNet and deep spectral clustering
0 -- 0Juntao Li, Shan Xiang, Dongqing Wei. Deciphering progressive lesion areas in breast cancer spatial transcriptomics via TGR-NMF
0 -- 0Elisabet Munté, Carla Roca, Jesús del Valle, Lidia Feliubadaló, Marta Pineda, Bernat Gel, Elisabeth Castellanos, Barbara Rivera, David Cordero, Víctor Moreno, Conxi Lázaro, José Marcos Moreno-Cabrera. Detection of germline CNVs from gene panel data: benchmarking the state of the art
0 -- 0Xinlong Wen, Hao Liu 0056, Wenhan Long, Shuoying Wei, Rongbo Zhu. Consistent semantic representation learning for out-of-distribution molecular property prediction
0 -- 0Bo Yang, Chenxi Cui, Meng Wang, Hong Ji, Feiyue Gao. Multi-view multi-level contrastive graph convolutional network for cancer subtyping on multi-omics data
0 -- 0Zhen Wang, Yizhen Feng, Qingwen Tian, Ziqi Liu, Pengju Yan, Xiaolin Li. RNADiffFold: generative RNA secondary structure prediction using discrete diffusion models
0 -- 0Yonathan Schwammenthal, Tom Rabinowitz, Lina Basel-Salmon, Reut Tomashov-Matar, Noam Shomron. Noninvasive fetal genotyping using deep neural networks
0 -- 0. Correction to: HHOMR: a hybrid high-order moment residual model for miRNA-disease association prediction
0 -- 0Zheng Su, Mingyan Fang, Andrei Smolnikov, Fatemeh Vafaee, Marcel E. Dinger, Emily C. Oates. Post-transcriptional regulation supports the homeostatic expression of mature RNA
0 -- 0Fabio Cumbo, Simone Truglia, Emanuel Weitschek, Daniel Blankenberg. Feature selection with vector-symbolic architectures: a case study on microbial profiles of shotgun metagenomic samples of colorectal cancer
0 -- 0Yiru Pan, Xingyu Ji, Jiaqi You, Lu Li, Zhenping Liu, Xianlong Zhang, Zeyu Zhang, Maojun Wang. CSGDN: contrastive signed graph diffusion network for predicting crop gene-phenotype associations
0 -- 0Fatma S. Ahmed, Saleh K. H. Aly, Xiangrong Liu. NABP-BERT: NANOBODY®-antigen binding prediction based on bidirectional encoder representations from transformers (BERT) architecture
0 -- 0Dries Heylen, Murih Pusparum, Jurgis Kuliesius, Jim Wilson, Young-Chan Park, Jacek Jamiolkowski, Valentino D'onofrio, Dirk Valkenborg, Jan Aerts, Gökhan Ertaylan, Jef Hooyberghs. Synthetic plasma pool cohort correction for affinity-based proteomics datasets allows multiple study comparison
0 -- 0Anna Postovskaya, Koen Vercauteren, Pieter Meysman, Kris Laukens. tcrBLOSUM: an amino acid substitution matrix for sensitive alignment of distant epitope-specific TCRs
0 -- 0Yanming Wei, Tong Zhou, Yixiao Zhai, Liang Yu 0002, Quan Zou 0001. FORAlign: accelerating gap-affine DNA pairwise sequence alignment using FOR-blocks based on Four Russians approach with linear space complexity
0 -- 0Ashwin Dhakal, Rajan Gyawali, Liguo Wang, Jianlin Cheng. Artificial intelligence in cryo-EM protein particle picking: recent advances and remaining challenges
0 -- 0Arnaud Guille, José Adélaïde, Pascal Finetti, Fabrice André, Daniel Birnbaum, Emilie Mamessier, François Bertucci, Max Chaffanet. A benchmarking study of individual somatic variant callers and voting-based ensembles for whole-exome sequencing
0 -- 0Zhijian Huang, Kai Chen, Xiaojun Xiao, Ziyu Fan, Yuanpeng Zhang, Lei Deng 0002. DeepHeteroCDA: circRNA-drug sensitivity associations prediction via multi-scale heterogeneous network and graph attention mechanism
0 -- 0Dao-Tran, Ha Nguyen, Van-Dung Pham, Phuong Nguyen, Hung Nguyen Luu, Liem Minh Phan, Christin Blair Destefano, Sai-Ching Jim Yeung, Tin Nguyen. A comprehensive review of cancer survival prediction using multi-omics integration and clinical variables
0 -- 0Iljung Jin, SongYeon Lee, Martin Schmuhalek, Hojung Nam. DD-PRiSM: a deep learning framework for decomposition and prediction of synergistic drug combinations
0 -- 0Liu Yang, Suqi Cao, Lei Liu 0033, Ruixin Zhu, Dingfeng Wu. cyclicpeptide: a Python package for cyclic peptide drug design
0 -- 0Qianwen Luo, Shanshan Zhang, Hamza Butt, Yin Chen, Hongmei Jiang, Lingling An. PhyImpute and UniFracImpute: two imputation approaches incorporating phylogeny information for microbial count data
0 -- 0Qi-xin Zhang, Tianneng Zhu, Feng Lin, Dunhuang Fang, Xuejun Chen, Xiangyang Lou, Zhijun Tong, Bingguang Xiao, Hai-ming Xu. mmGEBLUP: an advanced genomic prediction scheme for genetic improvement of complex traits in crops through integrative analysis of major genes, polygenes, and genotype-environment interactions
0 -- 0Marek Nowicki, Magdalena Mroczek, Dhananjay Mukhedkar, Piotr Bala, Ville Nikolai Pimenoff, Laila Sara Arroyo Mühr. HPV-KITE: sequence analysis software for rapid HPV genotype detection
0 -- 0Yun Zuo 0001, Xingze Fang, Jiankang Chen, Jiayi Ji, Yuwen Li, Zeyu Wu, Xiangrong Liu, Xiangxiang Zeng, Zhaohong Deng, Hongwei Yin, Anjing Zhao. MlyPredCSED: based on extreme point deviation compensated clustering combined with cross-scale convolutional neural networks to predict multiple lysine sites in human
0 -- 0Anna Postovskaya, Koen Vercauteren, Pieter Meysman, Kris Laukens. tcrBLOSUM: an amino acid substitution matrix for sensitive alignment of distant epitope-specific TCRs
0 -- 0Wengyu Zhang, Qi Tian 0001, Yi Cao, Wenqi Fan, Dongmei Jiang, Yaowei Wang 0001, Qing Li 0001, Xiao-Yong Wei. GraphATC: advancing multilevel and multi-label anatomical therapeutic chemical classification via atom-level graph learning
0 -- 0Aimin Xie, Hao Wang, Jiaxu Zhao, Zhaoyang Wang, Jinyuan Xu, Yan Xu. scPAS: single-cell phenotype-associated subpopulation identifier
0 -- 0Sehi Park, Kil To Chong 0001, Hilal Tayara. CpGFuse: a holistic approach for accurate identification of methylation states of DNA CpG sites
0 -- 0Willem Stock, Coralie Rousseau, Glen Dierickx, Sofie D'hondt, Luz Amadei Martínez, Simon M. Dittami, Luna M. van der Loos, Olivier De Clerck. Breaking free from references: a consensus-based approach for community profiling with long amplicon nanopore data
0 -- 0Shyamsundar Ravishankar, Vilma Perez, Roberta Davidson, Xavier Roca-Rada, Divon Lan, Yassine Souilmi, Bastien Llamas. Filtering out the noise: metagenomic classifiers optimize ancient DNA mapping
0 -- 0Ezechiel B. Tibiri, Palwende R. Boua, Issiaka Soulama, Christine Dubreuil-Tranchant, Ndomassi Tando, Charlotte Tollenaere, Christophe Brugidou, Romaric K. Nanema, Fidèle Tiendrebeogo. Challenges and opportunities of developing bioinformatics platforms in Africa: the case of BurkinaBioinfo at Joseph Ki-Zerbo University, Burkina Faso
0 -- 0Tianjiao Zhang, Zhongqian Zhao, Jixiang Ren, Ziheng Zhang, Hongfei Zhang, Guohua Wang. cfDiffusion: diffusion-based efficient generation of high quality scRNA-seq data with classifier-free guidance
0 -- 0Quan Lu, Jiajun Xu, Renyi Zhang, Hangcheng Liu, Meng Wang, Xiaoshuang Liu, Zhenyu Yue, Yujia Gao. RiceSNP-ABST: a deep learning approach to identify abiotic stress-associated single nucleotide polymorphisms in rice
0 -- 0Xianliang Liu, Jiawei Luo, Xinyan Wang, Yang Zhang, Junjie Chen. Directed evolution of antimicrobial peptides using multi-objective zeroth-order optimization
0 -- 0Le Yang, Runpu Chen, Steve Goodison, Yijun Sun. A comprehensive benchmark study of methods for identifying significantly perturbed subnetworks in cancer
0 -- 0Fu Liu, Zhimiao Zhao, Yun Liu. PHPGAT: predicting phage hosts based on multimodal heterogeneous knowledge graph with graph attention network
0 -- 0Shunying Liu, Lingfei Li, Yi Liang, Yang Tan, Xiaoyu Wang, Yanhai Feng, Nian Chen, Xia Lei. Novel genetic insight for psoriasis: integrative genome-wide analyses in 863 080 individuals and proteome-wide Mendelian randomization
0 -- 0Yves Gaetan Nana Teukam, Federico Zipoli, Teodoro Laino, Emanuele Criscuolo, Francesca Grisoni, Matteo Manica. Integrating genetic algorithms and language models for enhanced enzyme design
0 -- 0Jammi Prasanthi Sirasani, Cory Gardner, Gihwan Jung, Hyunju Lee, Tae-Hyuk Ahn. Bioinformatic approaches to blood and tissue microbiome analyses: challenges and perspectives
0 -- 0Mianyan Li, Thomas Hall, David E. MacHugh, Liang Chen, Dorian Garrick, Lixian Wang, Fuping Zhao. KPRR: a novel machine learning approach for effectively capturing nonadditive effects in genomic prediction
0 -- 0Xintian Xu, Rui Li, Ouyang Mo, Kai Liu, Justin Li, Pei Hao. Cell-type deconvolution for bulk RNA-seq data using single-cell reference: a comparative analysis and recommendation guideline
0 -- 0Junning Feng, Yong Liang, Tianwei Yu. ADM: adaptive graph diffusion for meta-dimension reduction
0 -- 0Chelsea Chen Yuge, Ee Soon Hang, Madasamy Ravi Nadar Mamtha, Shashikant Vishwakarma, Sijia Wang, Cheng Wang, Nguyen-Quoc-Khanh Le. RNA-ModX: a multilabel prediction and interpretation framework for RNA modifications
0 -- 0You Wu, Pengfei Xu, Liyuan Wang, Shuai Liu, Yingnan Hou, Hui Lu, Peng Hu, Xiaofei Li, Xiang Yu. scGO: interpretable deep neural network for cell status annotation and disease diagnosis
0 -- 0Xiaotao Shen, Songjie Chen, Liang Liang, Monika Avina, Hanyah Zackriah, Laura Jelliffe-Pawlowski, Larry Rand, Michael P. Snyder. Longitudinal urine metabolic profiling and gestational age prediction in human pregnancy
0 -- 0Geyan Ye, Xibao Cai, Houtim Lai, Xing Wang 0007, Junhong Huang, Longyue Wang, Wei Liu 0005, Xiangxiang Zeng. DrugAssist: a large language model for molecule optimization
0 -- 0Ivan Ferrari, Federica De Grossi, Giancarlo Lai, Stefania Oliveto, Giorgia Deroma, Stefano Biffo, Nicola Manfrini. CancerHubs: a systematic data mining and elaboration approach for identifying novel cancer-related protein interaction hubs
0 -- 0Peng Liu, Yuchen Pan, Hung-Ching Chang, Wenjia Wang, Yusi Fang, Xiangning Xue, Jian Zou, Jessica M. Toothaker, Oluwabunmi Olaloye, Eduardo Gonzalez Santiago, Black McCourt, Vanessa Mitsialis, Pietro Presicce, Suhas G. Kallapur, Scott B. Snapper, Jia-Jun Liu, George C. Tseng, Liza Konnikova, Silvia Liu. Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating
0 -- 0Luciano I Zablocki, Leandro A Bugnon, Matias Gerard, Leandro E. Di Persia, Georgina Stegmayer, Diego H. Milone. Comprehensive benchmarking of large language models for RNA secondary structure prediction
0 -- 0Xiangfei Zhou, Hao Wu. scHiClassifier: a deep learning framework for cell type prediction by fusing multiple feature sets from single-cell Hi-C data
0 -- 0Shilong Wang, Hai Cui, Yanchen Qu, Yijia Zhang. Multi-source biological knowledge-guided hypergraph spatiotemporal subnetwork embedding for protein complex identification
0 -- 0Sangmin Seo, Hwanhee Kim, Jieun Lee, Seungyeon Choi, Sanghyun Park. Exploring the potential of compound-protein complex structure-free models in virtual screening using BlendNet
0 -- 0Cathal Ormond, Niamh M. Ryan, Mathieu Cap, William Byerley, Aiden P. Corvin, Elizabeth A. Heron. BICEP: Bayesian inference for rare genomic variant causality evaluation in pedigrees
0 -- 0Jing Li, Qinglin Mei, Chaoxia Yang, Naibo Zhu, Guojun Li. TransBic: bucket trend-preserving biclustering for finding local and interpretable expression patterns
0 -- 0Uwaise Ibna Islam, Andre Luiz Campelo dos Santos, Ria Kanjilal, Raquel Assis. Learning genotype-phenotype associations from gaps in multi-species sequence alignments
0 -- 0Zhenxian Zheng, Yingxuan Ren, Lei Chen 0072, Angel On Ki Wong, Shumin Li, Xian Yu, Tak Wah Lam, Ruibang Luo. Repun: an accurate small variant representation unification method for multiple sequencing platforms
0 -- 0Genhui Zheng, Dingfeng Wu, Xiuxia Wei, Dongpo Xu, Tiantian Mao, Deyu Yan, Wenhao Han, Xiaoxiao Shang, Zikun Chen, Jingxuan Qiu, Kailin Tang, Zhiwei Cao, Tianyi Qiu. PbsNRs: predict the potential binders and scaffolds for nuclear receptors
0 -- 0Ruiqian Yao, Lu Sun, Ruifang Gao, Yue-mei, Geng Xue, Dong Yu. PTTM: dissecting the profile of tumor tissue microbiome to reveal microbiota features and associations with host transcriptome
0 -- 0Luca Cattelani, Vittorio Fortino. Dual-stage optimizer for systematic overestimation adjustment applied to multi-objective genetic algorithms for biomarker selection
0 -- 0Junxi Xie, Xiaopeng Jin, Hang Wei, Saisai Sun, Yumeng Liu. IDP-EDL: enhancing intrinsically disordered protein prediction by combining protein language model and ensemble deep learning
0 -- 0Chunying Wang, Di Zhang, Yuexin Ma, Yonghao Zhao, Ping Liu, Xiang Li. WheatGP, a genomic prediction method based on CNN and LSTM
0 -- 0Yang Yang, Zixuan Zheng, Yuyang Xu, Huifang Wei, Wenying Yan. BioGSF: a graph-driven semantic feature integration framework for biomedical relation extraction
0 -- 0Shuhe Liu, Zhen Wei, Daniel F. Carr, John Moraros. Deciphering the genetic interplay between depression and dysmenorrhea: a Mendelian randomization study
0 -- 0Xikang Feng, Miaozhe Huo, He Li, Yongze Yang, Yuepeng Jiang, Liang He, Shuai Cheng Li. A comprehensive benchmarking for evaluating TCR embeddings in modeling TCR-epitope interactions
0 -- 0Alida Zárate, Lorena Díaz-González, Blanca Taboada. VirDetect-AI: a residual and convolutional neural network-based metagenomic tool for eukaryotic viral protein identification
0 -- 0Alfred Ultsch, Jörn Lötsch. Augmenting small biomedical datasets using generative AI methods based on self-organizing neural networks
0 -- 0Gang Wen, Limin Li. Federated transfer learning with differential privacy for multi-omics survival analysis
0 -- 0Shuailin Xue, Fangfang Zhu, Jinyu Chen, Wenwen Min. Inferring single-cell resolution spatial gene expression via fusing spot-based spatial transcriptomics, location, and histology using GCN
0 -- 0Zexuan Wang, Qipeng Zhan, Shu Yang, Shizhuo Mu, Jiong Chen, Sumita Garai, Patryk Orzechowski, Joost B. Wagenaar, Li Shen 0001. QOT: Quantized Optimal Transport for sample-level distance matrix in single-cell omics
0 -- 0Zheyu Ding, Rong Wei, Jianing Xia, Yonghao Mu, Jiahuan Wang, Yingying Lin. Exploring the potential of large language model-based chatbots in challenges of ribosome profiling data analysis: a review
0 -- 0Marco Antônio M. Pretti, Gustavo Fioravanti Vieira, Mariana Boroni, Martín H. Bonamino. Unveiling cross-reactivity: implications for immune response modulation in cancer
0 -- 0Siwei Wu, Chaoyi Yin, Yuezhu Wang, Huiyan Sun. Identifying cancer prognosis genes through causal learning
0 -- 0Jin Zhang, Yan Yang, Muheng Shang, Lei Guo, Daoqiang Zhang, Lei Du. Mutual-assistance learning for trustworthy biomarker discovery and disease prediction
0 -- 0Rui Niu, Jingwei Wang, Yanli Li, Jiren Zhou, Yang Guo, Xuequn Shang 0001. Attention-aware differential learning for predicting peptide-MHC class I binding and T cell receptor recognition
0 -- 0Hai Cui, Meiyu Duan, Haijia Bi, Xiaobo Li 0007, Xiaodi Hou, Yi-Jia Zhang 0001. Heterogeneous graph contrastive learning with gradient balance for drug repositioning
0 -- 0Yuqi Miao, Huang Xu, Shuang Wang. PartIES: a disease subtyping framework with Partition-level Integration using diffusion-Enhanced Similarities from multi-omics Data
0 -- 0Jiachen Chen, Joanne M. Murabito, Kathryn L. Lunetta. ONDSA: a testing framework based on Gaussian graphical models for differential and similarity analysis of multiple omics networks
0 -- 0Hui Li, Lu Meng, Hongke Wang, Liang Cui, Heyu Sheng, Peiyan Zhao, Shuo Hong, Xinhua Du, Shi Yan, Yun Xing, Shicheng Feng, Yan Zhang, Huan Fang, Jing Bai, Yan Liu, Shaowei Lan, Tao Liu, Yanfang Guan, Xuefeng Xia, Xin Yi, Ying Cheng. Precise identification of somatic and germline variants in the absence of matched normal samples
0 -- 0Yushuang He, Feng Zhou, Jiaxing Bai, Yichun Gao, Xiaobing Huang, Ying Wang. ViTax: adaptive hierarchical viral taxonomy classification with a taxonomy belief tree on a foundation model
0 -- 0Ruogu Wang, Yunlong Feng, Alex M. Valm. A framework of multi-view machine learning for biological spectral unmixing of fluorophores with overlapping excitation and emission spectra
0 -- 0Cheng Han, Shanshan Fu, Miaomiao Chen, Yujie Gou, Dan Liu, Chi Zhang, Xinhe Huang, Leming Xiao, Miaoying Zhao, Jiayi Zhang, Qiang Xiao, Di Peng, Yu Xue 0001. GPSD: a hybrid learning framework for the prediction of phosphatase-specific dephosphorylation sites
0 -- 0Xiaoyi Li, Kangli Zhu, Ying Zhen. A versatile pipeline to identify convergently lost ancestral conserved fragments associated with convergent evolution of vocal learning
0 -- 0Yiwen Yang, Chengming Zhang 0003, Zhaonan Liu, Kazuyuki Aihara, Chuanchao Zhang, Luonan Chen, Wu Wei. MCGAE: unraveling tumor invasion through integrated multimodal spatial transcriptomics
0 -- 0Haicheng Li, Junhua Niu, Yalan Sheng, Yifan Liu, Shan Gao. SMAC: identifying DNA N6-methyladenine (6mA) at the single-molecule level using SMRT CCS data
0 -- 0Yuxuan Pang, Chunxuan Wang, Yao-zhong Zhang, Zhuo Wang, Seiya Imoto, Tzong-Yi Lee. STForte: tissue context-specific encoding and consistency-aware spatial imputation for spatially resolved transcriptomics
0 -- 0Cui-Xiang Lin, Hong-Dong Li, Jianxin Wang 0001. LIMO-GCN: a linear model-integrated graph convolutional network for predicting Alzheimer disease genes
0 -- 0Si Zheng 0001, Yaowen Gu, Yuzhen Gu, Yelin Zhao, Liang Li, Min Wang, Rui Jiang 0001, Xia Yu, Ting Chen, Jiao Li 0001. Machine learning-enabled virtual screening indicates the anti-tuberculosis activity of aldoxorubicin and quarfloxin with verification by molecular docking, molecular dynamics simulations, and biological evaluations
0 -- 0Lijun Cai, Guanyu Yue, Yifan Chen, Li Wang 0145, Xiaojun Yao, Quan Zou 0001, Xiangzheng Fu, Dong-Sheng Cao 0001. ET-PROTACs: modeling ternary complex interactions using cross-modal learning and ternary attention for accurate PROTAC-induced degradation prediction
0 -- 0Xin Ma, Lijing Lin, Qian Zhao, Mudassar Iqbal. TriTan: an efficient triple nonnegative matrix factorization method for integrative analysis of single-cell multiomics data
0 -- 0Qinglong Zhang, Liping Kang, Haoran Yang, Fei Liu, Xiaohui Wu. Supervised analysis of alternative polyadenylation from single-cell and spatial transcriptomics data with spvAPA
0 -- 0Harvard Wai Hann Hui, Wei Xin Chan, Wilson Wen Bin Goh. Assessing the impact of batch effect associated missing values on downstream analysis in high-throughput biomedical data
0 -- 0Yi Zhang, Jindi Huang, Xinze Li, Wenqi Sun, Nana Zhang, Jiquan Zhang, Tiegen Chen, Ling Wang. Self-awareness of retrosynthesis via chemically inspired contrastive learning for reinforced molecule generation
0 -- 0Nandhini Rajagopal, Udit Choudhary, Kenny Tsang, Kyle P. Martin, Murat Karadag, Hsin-Ting Chen, Na-Young Kwon, Joseph Mozdzierz, Alexander M. Horspool, Li Li, Peter M. Tessier, Michael S. Marlow, Andrew E. Nixon, Sandeep Kumar. Deep learning-based design and experimental validation of a medicine-like human antibody library
0 -- 0Giuseppe Defazio, Marco Antonio Tangaro, Graziano Pesole, Bruno Fosso. kMetaShot: a fast and reliable taxonomy classifier for metagenome-assembled genomes
0 -- 0Chenrui Duan, Zelin Zang, Yongjie Xu, Hang He, Siyuan Li 0002, Zihan Liu, Zhen Lei 0001, Ju-Sheng Zheng, Stan Z. Li. FGeneBERT: function-driven pre-trained gene language model for metagenomics
0 -- 0Bo Wang, Yahui Long, Yuting Bai, Jiawei Luo 0001, Chee-Keong Kwoh 0001. STCGAN: a novel cycle-consistent generative adversarial network for spatial transcriptomics cellular deconvolution
0 -- 0Liguo Ye, Cheng Ye, Pengtao Li, Yu Wang, Wenbin Ma. Inferring the genetic relationships between unsupervised deep learning-derived imaging phenotypes and glioblastoma through multi-omics approaches
0 -- 0Yueer Li, Chen Peng, Fei Chi, Zinuo Huang, Mengyi Yuan, Xin Zhou, Chao Jiang. The iPhylo suite: an interactive platform for building and annotating biological and chemical taxonomic trees
0 -- 0Lingsheng Cai, Xiuli Ma, Jianzhu Ma. Integrating scRNA-seq and scATAC-seq with inter-type attention heterogeneous graph neural networks
0 -- 0. Correction to: Unveiling cross-reactivity: implications for immune response modulation in cancer
0 -- 0Jiaojiao Guan, Yongxin Ji, Cheng Peng, Wei Zou, Xubo Tang, Jiayu Shang, Yanni Sun. GOPhage: protein function annotation for bacteriophages by integrating the genomic context
0 -- 0Pengcheng Yang, Youngwoo Lee, Daniel B. Szymanski, Jun Xie. Integrating CORUM and co-fractionation mass spectrometry to create enhanced benchmarks for protein complex predictions
0 -- 0Jinyu Chen, Wenwen Min. sTPLS: identifying common and specific correlated patterns under multiple biological conditions
0 -- 0Mengya Liu, Zhan-Li Sun, Zhigang Zeng, Kin-Man Lam 0001. N6-methyladenine sites
0 -- 0Wenjie Sun, Daphne van Ginneken, Leïla Perié. scMitoMut for calling mitochondrial lineage-related mutations in single cells
0 -- 0Marin Volaric, Nevenka Mestrovic, Evelin Despot-Slade. SatXplor - a comprehensive pipeline for satellite DNA analyses in complex genome assemblies
0 -- 0George Assaf, Fei Liu 0006, Monika Heiner. Incremental modelling and analysis of biological systems with fuzzy hybrid Petri nets
0 -- 0Shijie Luo, Ming Zhu, Liquan Lin, Jiajing Xie, Shihao Lin, Ying Chen, Jiali Zhu, Jialiang Huang. DECA: harnessing interpretable transformer model for cellular deconvolution of chromatin accessibility profile
0 -- 0Olivier Cinquin. Steering veridical large language model analyses by correcting and enriching generated database queries: first steps toward ChatGPT bioinformatics
0 -- 0Tingpeng Yang, Yonghong He, Yu Wang. Introducing TEC-LncMir for prediction of lncRNA-miRNA interactions through deep learning of RNA sequences
0 -- 0Sara Cuvertino, Terence Garner, Evgenii Martirosian, Bridgious Walusimbi, Susan J. Kimber, Siddharth Banka, Adam Stevens. Higher order interaction analysis quantifies coordination in the epigenome revealing novel biological relationships in Kabuki syndrome
0 -- 0Elena Domínguez Romero, Stanislav Mazurenko, Martin Scheringer, Vítor A. P. Martins dos Santos, Chris T. A. Evelo, Mihail Anton, John M. Hancock, Anze Zupanic, María Suárez-Diez. Response to Letter to Editor by A. Derbalah et al.: the role of automation in enhancing reproducibility and interoperability of PBPK models
0 -- 0Kaiyuan Yang 0009, Jiabei Cheng, Shenghao Cao, Xiaoyong Pan, Hong-bin Shen, Ye Yuan. Predicting transcriptional changes induced by molecules with MiTCP
0 -- 0Cheng Tan 0012, Yijie Zhang, Zhangyang Gao, Hanqun Cao, Siyuan Li 0002, Siqi Ma, Mathieu Blanchette, Stan Z. Li. R3Design: deep tertiary structure-based RNA sequence design and beyond
0 -- 0Xizi Luo, Amadeus Song Yi Chi, Andre Huikai Lin, Tze Jet Ong, Limsoon Wong, Chowdhury Rafeed Rahman. Benchmarking recent computational tools for DNA-binding protein identification
0 -- 0Yiwen Wei, Tianyi Qiu, Yisi Ai, Yuxi Zhang, Junting Xie, Dong Zhang, Xiaochuan Luo, Xiulan Sun, Xin Wang, Jingxuan Qiu. Advances of computational methods enhance the development of multi-epitope vaccines
0 -- 0Yiyang Zhu, Wenying Chen, Kexuan Zhu, Yuxin Liu, Shuiping Huang, Ping Zeng. Polygenic prediction for underrepresented populations through transfer learning by utilizing genetic similarity shared with European populations
0 -- 0Ankang Wei, Huanghan Zhan, Zhen Xiao, Weizhong Zhao, Xingpeng Jiang. A novel framework for phage-host prediction via logical probability theory and network sparsification
0 -- 0Sushmita Basu, Jing Yu, Daisuke Kihara, Lukasz A. Kurgan. Twenty years of advances in prediction of nucleic acid-binding residues in protein sequences
0 -- 0Chen M. Chen, Rosemary Yu. A multi-step completion process model of cell plasticity
0 -- 0Jin Han, Haohong Zhang, Kang Ning. Techniques for learning and transferring knowledge for microbiome-based classification and prediction: review and assessment
0 -- 0James Strudwick, Laura-Jayne Gardiner, Kate Denning-James, Niina Haiminen, Ashley Evans, Jennifer Kelly, Matthew Madgwick, Filippo Utro, Ed Seabolt, Christopher Gibson, Bharat Bedi, Daniel Clayton, Ciaron Howell, Laxmi Parida, Anna Paola Carrieri. AutoXAI4Omics: an automated explainable AI tool for omics and tabular data
0 -- 0Baiming Zou, James G. Xenakis, Meisheng Xiao, Apoena Aguiar Ribeiro, Kimon Divaris, Di Wu, Fei Zou. A deep learning feature importance test framework for integrating informative high-dimensional biomarkers to improve disease outcome prediction
0 -- 0Andrea Lomagno, Ishak Yusuf, Gabriele Tosadori, Dario Bonanomi, Pietro Luigi Mauri, Dario Di Silvestre. CoPPIs algorithm: a tool to unravel protein cooperative strategies in pathophysiological conditions
0 -- 0Xiaoqing Ru, Shulin Zhao, Quan Zou, Lifeng Xu. Identify potential drug candidates within a high-quality compound search space
0 -- 0Xinyi Mou, Haoyu Du, Guanghua Qiao, Jing Li. Evaluation of imputation and imputation-free strategies for differential abundance analysis in metaproteomics data
0 -- 0Qiaolin Lu, Jiayuan Ding, Lingxiao Li, Yi Chang 0001. Graph contrastive learning of subcellular-resolution spatial transcriptomics improves cell type annotation and reveals critical molecular pathways
0 -- 0QiQi Lu, Zhixian Liu, Xiaosheng Wang. Inferring tumor purity using multi-omics data based on a uniform machine learning framework MoTP
0 -- 0Leandro Murgas, Gianluca Pollastri, Erick Riquelme, Mauricio Sáez, Alberto J. M. Martin. Understanding relationships between epigenetic marks and their application to robust assignment of chromatin states
0 -- 0Yizhen Wang, Li Cheng 0007, Yanyun Zhang, Yujia Cao, Daniyal M. Al-Ghazzawi. DEKP: a deep learning model for enzyme kinetic parameter prediction based on pretrained models and graph neural networks
0 -- 0Hao Yuan, Parker Hicks, Mansooreh Ahmadian, Kayla A. Johnson, Lydia Valtadoros, Arjun Krishnan. Annotating publicly-available samples and studies using interpretable modeling of unstructured metadata
0 -- 0Nana Jin, Chuanchuan Nan, Wanyang Li, Peijing Lin, Yu Xin, Jun Wang, Yuelong Chen, Yuanhao Wang, Kaijiang Yu, Changsong Wang, Chunbo Chen, Qingshan Geng, Lixin Cheng. PAGE-based transfer learning from single-cell to bulk sequencing enhances model generalization for sepsis diagnosis
0 -- 0Zhilong Liu, Hai Lin, Xiang Li, Hao Xue, Yuer Lu, Fei Xu, Jianwei Shuai. The network structural entropy for single-cell RNA sequencing data during skin aging
0 -- 0Yixuan Wang, Yanfang Guan, Xin Lai, Yuqian Liu, Zhili Chang, Xiaonan Wang, Quan Wang, Jingjing Liu, Jian Zhao, Shuanying Yang, Jiayin Wang, Xiaofeng Song. THOR: a TMB heterogeneity-adaptive optimization model predicts immunotherapy response using clonal genomic features in group-structured data
0 -- 0Lin Yuan 0001, Shengguo Sun, Yufeng Jiang, Qinhu Zhang, Lan Ye, Chun-Hou Zheng 0001, De-Shuang Huang. scRGCL: a cell type annotation method for single-cell RNA-seq data using residual graph convolutional neural network with contrastive learning
0 -- 0Fengyue Zhang, Xuqi Zhao, Jinrui Wei, Lichuan Wu. PathSynergy: a deep learning model for predicting drug synergy in liver cancer
0 -- 0Donghan Wang, Xu Dong, Xueyou Zhang, Lihong Hu. GADIFF: a transferable graph attention diffusion model for generating molecular conformations
0 -- 0Xin Ma, Lijing Lin, Qian Zhao, Mudassar Iqbal. TriTan: an efficient triple nonnegative matrix factorization method for integrative analysis of single-cell multiomics data
0 -- 0Hao Lu, Mostafa Rezapour, Haseebullah Baha, Muhammad Khalid Khan Niazi, Aarthi Narayanan, Metin Nafi Gürcan. P-value computation
0 -- 0Juho Pelto, Kari Auranen, Janne V. Kujala, Leo Lahti. Elementary methods provide more replicable results in microbial differential abundance analysis
0 -- 0Jiancheng Zhong, Zhiwei Zou, Jie Qiu, Shaokai Wang. ScFold: a GNN-based model for efficient inverse folding of short-chain proteins via spatial reduction
0 -- 0Yi Zhang 0044, Yin Wang, Xinyuan Liu, Xi Feng. CPARI: a novel approach combining cell partitioning with absolute and relative imputation to address dropout in single-cell RNA-seq data
0 -- 0Jiajian Luo, Jiye Fu, Zuhong Lu, Jing Tu. Deep learning in integrating spatial transcriptomics with other modalities
0 -- 0Abdallah Derbalah, Masoud Jamei, Iain Gardner, Armin Sepp. The role of automation in enhancing reproducibility and interoperability of PBPK models
0 -- 0Wendong Huang, Yaofeng Hu, Lequn Wang, Guangsheng Wu, Chuanchao Zhang, Qianqian Shi. Spatially aligned graph transfer learning for characterizing spatial regulatory heterogeneity
0 -- 0Xinglong Wang, Kangjie Xu, Lingling Ma, Ruoxi Sun, Kun Wang, Ruiyan Wang, Junli Zhang, Wenwen Tao, Kai Linghu, Shuyao Yu, Jingwen Zhou. Diffusion model assisted designing self-assembling collagen mimetic peptides as biocompatible materials
0 -- 0Tong Lu, Wei Guo, Wei Guo, Wangyang Meng, Tianyi Han, Zizhen Guo, Chengqiang Li, Shugeng Gao, Youqiong Ye, Hecheng Li. A novel computational model ITHCS for enhanced prognostic risk stratification in ESCC by correcting for intratumor heterogeneity
0 -- 0Hongtao Yu, Guojing He, Wei Wang, Senbiao Qin, Yu Wang, Mingze Bai, Kunxian Shu, Dan Pu. A graph neural network approach for accurate prediction of pathogenicity in multi-type variants
0 -- 0Pawel Dudzic, Bartosz Janusz, Tadeusz Satlawa, Dawid Chomicz, Tomasz Gawlowski, Rafal Grabowski, Przemek Józwiak, Mateusz Tarkowski, Maciej Mycielski, Sonia Wróbel, Konrad Krawczyk. RIOT - Rapid Immunoglobulin Overview Tool - annotation of nucleotide and amino acid immunoglobulin sequences using an open germline database
0 -- 0Dongping Liu, Dinghao Liu, Kewei Sheng, Zhenyong Cheng, Zixuan Liu, Yanling Qiao, Shangxuan Cai, Yulong Li, Jubo Wang, Hongyang Chen, Chi Hu, Peng Xu, Bin Di, Jun Liao. STNGS: a deep scaffold learning-driven generation and screening framework for discovering potential novel psychoactive substances
0 -- 0Runqing Wang, Qiguo Dai, Xiaodong Duan, Quan Zou 0001. stHGC: a self-supervised graph representation learning for spatial domain recognition with hybrid graph and spatial regularization
0 -- 0Junhang Cao, Jun Zhang, Qiyuan Yu, Junkai Ji, JianQiang Li, Shan He, Zexuan Zhu. TG-CDDPM: text-guided antimicrobial peptides generation based on conditional denoising diffusion probabilistic model
0 -- 0Xueshi Yu, Renmin Han, Haitao Jiao, Wenjia Meng. Few-shot classification of Cryo-ET subvolumes with deep Brownian distance covariance
0 -- 0Tianjiao Zhang, Xiang Zhang, Zhenao Wu, Jixiang Ren, Zhongqian Zhao, Hongfei Zhang, Guohua Wang, Tao Wang 0082. VGAE-CCI: variational graph autoencoder-based construction of 3D spatial cell-cell communication network
0 -- 0Yinhu Li, Guangze Pan, Shuai Wang, Zhengtu Li, Ru Yang, Yiqi Jiang, Yu Chen, Shuaicheng Li 0001, Bairong Shen. Comprehensive human respiratory genome catalogue underlies the high resolution and precision of the respiratory microbiome
0 -- 0Xianxiao Zhou, Ling Wu, Minghui Wang, Guojun Wu, Bin Zhang. iDOMO: identification of drug combinations via multi-set operations for treating diseases
0 -- 0Sara Potente, Diego Boscarino, Dino Paladin, Sergio Marchini, Luca Beltrame, Chiara Romualdi. SAMURAI: shallow analysis of copy number alterations using a reproducible and integrated bioinformatics pipeline
0 -- 0Huan Yang, Minglei Yang, Jiani Chen, Guocong Yao, Quan Zou, Linpei Jia. Multimodal deep learning approaches for precision oncology: a comprehensive review
0 -- 0Yan-Yu Li, Fengcui Qian, Guo-Rui Zhang, Xue-Cang Li, Li-Wei Zhou, Zheng-Min Yu, Wei Liu, Qiu-Yu Wang, Chunquan Li 0002. FunlncModel: integrating multi-omic features from upstream and downstream regulatory networks into a machine learning framework to identify functional lncRNAs
0 -- 0James Strudwick, Laura-Jayne Gardiner, Kate Denning-James, Niina Haiminen, Ashley Evans, Jennifer Kelly, Matthew Madgwick, Filippo Utro, Ed Seabolt, Christopher Gibson, Bharat Bedi, Daniel Clayton, Ciaron Howell, Laxmi Parida, Anna Paola Carrieri. AutoXAI4Omics: an automated explainable AI tool for omics and tabular data
0 -- 0Long Xu, Qiang Yang 0015, Weihe Dong, Xiaokun Li, Kuanquan Wang, Suyu Dong, Xianyu Zhang, Tiansong Yang, Gongning Luo, Xingyu Liao, Xin Gao 0001, Guohua Wang. Meta learning for mutant HLA class I epitope immunogenicity prediction to accelerate cancer clinical immunotherapy
0 -- 0Ornit Nahman, Timothy J. Few-Cooper, Shai S. Shen-Orr. Cell-specific priors rescue differential gene expression in spatial spot-based technologies
0 -- 0Steffen Klamt, Jürgen Zanghellini, Axel von Kamp. Minimal cut sets in metabolic networks: from conceptual foundations to applications in metabolic engineering and biomedicine
0 -- 0Peng-Hsuan Li, Yih-Yun Sun, Hsueh-Fen Juan, Chien-Yu Chen 0001, Huai-Kuang Tsai, Jia-Hsin Huang. A large language model framework for literature-based disease-gene association prediction
0 -- 0Yinhu Li, Guangze Pan, Shuai Wang, Zhengtu Li, Ru Yang, Yiqi Jiang, Yu Chen, Shuaicheng Li 0001, Bairong Shen. Comprehensive human respiratory genome catalogue underlies the high resolution and precision of the respiratory microbiome
0 -- 0Yuejun Tan, Linhai Xie, Hong Yang, Qingyuan Zhang, Jinyuan Luo, Yanchun Zhang. BioDSNN: a dual-stream neural network with hybrid biological knowledge integration for multi-gene perturbation response prediction
0 -- 0Shuo Li, Pei Fen Kuan. A systematic evaluation of cell-type-specific differential methylation analysis in bulk tissue
0 -- 0Yongjie Xu, Zelin Zang, Bozhen Hu, Yue Yuan, Cheng Tan 0012, Jun Xia 0001, Stan Z. Li. Complex hierarchical structures analysis in single-cell data with Poincaré deep manifold transformation
0 -- 0. Correction to: Toward molecular diagnosis of major depressive disorder by plasma peptides using a deep learning approach
0 -- 0Shan Tharanga, Eyyüb Selim Ünlü, Yongli Hu, Muhammad Farhan Sjaugi, Muhammet A Çelik, Hilal Hekimoglu, Olivo Miotto, Muhammed Miran Öncel, Asif M. Khan. DiMA: sequence diversity dynamics analyser for viruses
0 -- 0Yunjian Chang, Ligang Wu. CapHLA: a comprehensive tool to predict peptide presentation and binding to HLA class I and class II
0 -- 0Ying Li 0004, Qifeng Hu, Siyu Han, Rui Wang-Sattler, Wei Du 0002. Multi-Manifolds fusing hyperbolic graph network balanced by pareto optimization for identifying spatial domains of spatial transcriptomics
0 -- 0Ankang Wei, Zhen Xiao, Lingling Fu, Weizhong Zhao, Xingpeng Jiang. Predicting phage-host interactions via feature augmentation and regional graph convolution
0 -- 0Boya Ji, Xiaoqi Wang, Xiang Wang, Liwen Xu, Shaoliang Peng. scDCA: deciphering the dominant cell communication assembly of downstream functional events from single-cell RNA-seq data
0 -- 0Zheyang Zhang, Ronghan Tang, Ming Zhu, Zhijuan Zhu, Jiali Zhu, Hua Li, Mengsha Tong, Nainong Li, Jialiang Huang. Deciphering cell states and the cellular ecosystem to improve risk stratification in acute myeloid leukemia
0 -- 0Yuanyuan Mo, Juan Liu, Lihua Zhang. Deconvolution of spatial transcriptomics data via graph contrastive learning and partial least square regression
0 -- 0Junlei Liao, Hongyang Yi, Hao Wang, Sumei Yang, Duanmei Jiang, Xin Huang, Mingxia Zhang, Jiayin Shen, Hongzhou Lu, Yuanling Niu. CDCM: a correlation-dependent connectivity map approach to rapidly screen drugs during outbreaks of infectious diseases
0 -- 0. Expression of Concern: Bioinformatics in Russia: history and present-day landscape
0 -- 0Johanna Elena Schmitz, Sven Rahmann. A comprehensive review and evaluation of species richness estimation
0 -- 0Elissavet Zacharopoulou, Maria D. Paraskevopoulou, Spyros Tastsoglou, Athanasios Alexiou, Anna Karavangeli, Vasileios Pierros, Stefanos Digenis, Galatea Mavromati, Artemis G. Hatzigeorgiou, Dimitra Karagkouni. microT-CNN: an avant-garde deep convolutional neural network unravels functional miRNA targets beyond canonical sites
0 -- 0Yinqiao Yan, Xiangyu Luo. BACT: nonparametric Bayesian cell typing for single-cell spatial transcriptomics data
0 -- 0Isaac Torres, Shufan Zhang, Amanda Bouffier, Michael Skaro, Yue Wu, Lauren Stupp, Jonathan P. Arnold, Y. Anny Chung, Heinz-Bernd Schüttler. MINE: a new way to design genetics experiments for discovery
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0 -- 0Xiangnan Xu, Alistair M. Senior, David G. Le Couteur, Victoria C. Cogger, David Raubenheimer, David E. James, Benjamin Parker, Stephen J. Simpson, Samuel Müller 0001, Jean Y. H. Yang. eNODAL: an experimentally guided nutriomics data clustering method to unravel complex drug-diet interactions
0 -- 0Tianjiao Zhang, Xiang Zhang, Zhenao Wu, Jixiang Ren, Zhongqian Zhao, Hongfei Zhang, Guohua Wang, Tao Wang 0082. VGAE-CCI: variational graph autoencoder-based construction of 3D spatial cell-cell communication network
0 -- 0Haoyang Cheng, Zhuoran Liang, Yijin Wu, Jiamin Hu, Bijin Cao, Zekun Liu, Bo Liu, Han Cheng, Ze-Xian Liu. Inferring kinase-phosphosite regulation from phosphoproteome-enriched cancer multi-omics datasets
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0 -- 0Zhen Wang, Yizhen Feng, Qingwen Tian, Ziqi Liu, Pengju Yan, Xiaolin Li. RNADiffFold: generative RNA secondary structure prediction using discrete diffusion models
0 -- 0Jing Liang, Zhuo Hu, Ying Bi, Han Cheng, Weifeng Guo. Multimodal multiobjective optimization with structural network control principles to optimize personalized drug targets for drug discovery of individual patients
0 -- 0Cristian Riccio, Max L. Jansen, Felix Thalén, Georgios Koliopanos, Vivian Link, Andreas Ziegler. Assessment of the functionality and usability of open-source rare variant analysis pipelines
0 -- 0Xiaoyi Li, Kangli Zhu, Ying Zhen. A versatile pipeline to identify convergently lost ancestral conserved fragments associated with convergent evolution of vocal learning
0 -- 0Ren Wang, Qiumei Liu, Wenhua You, Huiyu Wang, Yun Chen. A transformer-based deep learning survival prediction model and an explainable XGBoost anti-PD-1/PD-L1 outcome prediction model based on the cGAS-STING-centered pathways in hepatocellular carcinoma
0 -- 0Kaiwen Zhang, Yuhao Tao, Fei Wang. AntiBinder: utilizing bidirectional attention and hybrid encoding for precise antibody-antigen interaction prediction
0 -- 0Yiwen Yang, Chengming Zhang 0003, Zhaonan Liu, Kazuyuki Aihara, Chuanchao Zhang, Luonan Chen, Wu Wei. MCGAE: unraveling tumor invasion through integrated multimodal spatial transcriptomics
0 -- 0Chi Zhang, Yiran Cheng, Kaiwen Feng, Fa Zhang 0001, Renmin Han, Jieqing Feng. UPicker: a semi-supervised particle picking transformer method for cryo-EM micrographs
0 -- 0Lubin Cui, Guiliang Guo, Michael K. Ng, Quan Zou 0001, Yushan Qiu. GSTRPCA: irregular tensor singular value decomposition for single-cell multi-omics data clustering
0 -- 0Yuhan Wang, Zhikang Wang, Xuan Yu, Xiaoyu Wang, Jiangning Song, Dong-jun Yu, Fang Ge. MORE: a multi-omics data-driven hypergraph integration network for biomedical data classification and biomarker identification
0 -- 0Anqiang Ye, Ji-Yun Zhang, Qian Xu, Hai-Xia Guo, Zhen Liao, Hongtu Cui, DongDong Zhang, Feng-Biao Guo. Carmna: classification and regression models for nitrogenase activity based on a pretrained large protein language model
0 -- 0Chun Shen Lim, Alexandra K. Gibbon, Anh Thu Tran Nguyen, Gabrielle S. W. Chieng, Chris M. Brown. RIBOSS detects novel translational events by combining long- and short-read transcriptome and translatome profiling
0 -- 0Konstantina Tzavella, Adrián Díaz, Catharina Olsen, Wim F. Vranken. Combining evolution and protein language models for an interpretable cancer driver mutation prediction with D2Deep
0 -- 0Luuk R. Hoegen Dijkhof, Teemu K. E. Rönkkö, Hans C. von Vegesack, Jacob Lenzing, Alexander S. Hauser. Deep learning in GPCR drug discovery: benchmarking the path to accurate peptide binding
0 -- 0Aoyi Wang, Haoyang Peng, Yingdong Wang, Haoran Zhang, Caiping Cheng, Jinzhong Zhao, Wuxia Zhang, Jianxin Chen, Peng Li 0004. NP-TCMtarget: a network pharmacology platform for exploring mechanisms of action of traditional Chinese medicine
0 -- 0Yong Liu, Le Zhong, Bin Yan, Zhuobin Chen, Yanjia Yu, Dan Yu, Jing Qin 0004, Junwen Wang. A self-attention-driven deep learning framework for inference of transcriptional gene regulatory networks
0 -- 0Matee Ullah, Shahid Akbar, Ali Raza, Kashif Ahmad Khan, Quan Zou 0001. TargetCLP: clathrin proteins prediction combining transformed and evolutionary scale modeling-based multi-view features via weighted feature integration approach
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0 -- 0Nanhai Jiang, Yang Wu, Steven G. Rozen. Benchmarking 13 tools for mutational signature attribution, including a new and improved algorithm
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0 -- 0Mingguang Shi, Xuefeng Li. Addressing scalability and managing sparsity and dropout events in single-cell representation identification with ZIGACL
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0 -- 0Linjie Wang, Huixia Zhang, Bo Yi, Weidong Xie, Kun Yu 0002, Wei Li 0117, Keqin Li, Dazhe Zhao. FactVAE: a factorized variational autoencoder for single-cell multi-omics data integration analysis
0 -- 0Han Wang, Zilin Ren, Jinghong Sun, Yongbing Chen, Xiaochen Bo, Jiguo Xue, Jingyang Gao, Ming Ni. DeepPFP: a multi-task-aware architecture for protein function prediction
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0 -- 0Kris Sankaran, Saritha Kodikara, Jingyi Jessica Li, Kim-Anh Lê Cao. Semisynthetic simulation for microbiome data analysis
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0 -- 0Yutao Zhang, Haocheng Ding, Zhiguang Huo, Li Chen. A novel Bayesian hierarchical model for detecting differential circadian pattern in transcriptomic applications
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0 -- 0Yiren Shao, Qi Gao, Liuyang Wang, Dongmei Li, Andrew B. Nixon, Cliburn Chan, Qi-Jing Li, Jichun Xie. B-Lightning: using bait genes for marker gene hunting in single-cell data with complex heterogeneity
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0 -- 0Ashok Kumar, Sonia Chadha, Mradul Sharma, Mukesh Kumar. Deciphering optimal molecular determinants of non-hemolytic, cell-penetrating antimicrobial peptides through bioinformatics and Random Forest
0 -- 0Yixuan Qiao, Hong Zhou, Yang Liu, Ruixuan Chen, Xiaodong Zhang, Sheng Nie, Fan Fan Hou, Yi Zhao, Xin Xu, Lianhe Zhao. A multi-modal fusion model with enhanced feature representation for chronic kidney disease progression prediction
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0 -- 0. Correction to: BANMF-S: a blockwise accelerated non-negative matrix factorization framework with structural network constraints for single cell imputation
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0 -- 0Yunlong Wang, Siyuan Kong, Cong Zhou, Yanfang Wang, Yubo Zhang, Yaping Fang, Guoliang Li 0002. A review of deep learning models for the prediction of chromatin interactions with DNA and epigenomic profiles
0 -- 0Xiaolong Wu, Lehan Zhang, Xiaochu Tong, Yitian Wang, Zimei Zhang, Xiangtai Kong, Shengkun Ni, Xiaomin Luo, Mingyue Zheng, Yun Tang 0001, Xutong Li. miCGR: interpretable deep neural network for predicting both site-level and gene-level functional targets of microRNA
0 -- 0Gen Li, Sijie Yao, Long Fan. Shared-weight graph framework for comprehensive protein stability prediction across diverse mutation types
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0 -- 0Lan Cao, Wenhao Zhang, Fan Yang, Shengquan Chen, Xiaobing Huang, Feng Zeng, Ying Wang. BIOTIC: a Bayesian framework to integrate single-cell multi-omics for transcription factor activity inference and improve identity characterization of cells
0 -- 0José A. Sánchez-Villanueva, Lia N'guyen, Mathilde Poplineau, Estelle Duprez, Elisabeth Remy, Denis Thieffry. Predictive modelling of acute Promyelocytic leukaemia resistance to retinoic acid therapy
0 -- 0Ansar Naseem, Fahad Alturise, Tamim Alkhalifah, Yaser Daanial Khan. ESM-BBB-Pred: a fine-tuned ESM 2.0 and deep neural networks for the identification of blood-brain barrier peptides
0 -- 0Zeyin Li, Min Wang, Songge Li, Fangyuan Shi. MIRACN: a residual convolutional neural network for predicting cell line specific functional regulatory variants
0 -- 0Meng-Chi Chung, Li-Jen Su, Chien-Lin Chen, Li-Ching Wu. Revealing the antimicrobial potential of traditional Chinese medicine through text mining and molecular computation
0 -- 0Jiaqi Wang, Ronggang Xi, Yi Wang, Huiyuan Gao, Ming Gao, Xiaozhe Zhang, Lihua Zhang, Yukui Zhang. Toward molecular diagnosis of major depressive disorder by plasma peptides using a deep learning approach
0 -- 0Hong Xia, Boya Ji, Debin Qiao, Shaoliang Peng. CellMsg: graph convolutional networks for ligand-receptor-mediated cell-cell communication analysis